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- merck millipore,默克密理博,ABE333,Anti-MeCP2 Antibody, Isoform B
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABE333 描述 Anti-MeCP2 Antibody, Isoform B Alternate Names - MeCp2
- Methyl-CpG-binding protein 2
- MeCp-2 protein
背景信息 DNA methyltransferases methylate the 5-position of cytosine in the context of CpG dinucleotides. DNA methylation is crucial for normal embryonic development, imprinting, and X chromosome inactivation. Methyl CpG binding proteins (MeCPs) specifically recognize methylated regions of DNA and repress transcription both directly and by association with known corepressor proteins which include members of the histone deacetylase protein families. 产品信息 格式 Affinity Purified 控制 - MCF7 cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect MeCP2 using this rabbit polyclonal antibody, Anti-MeCP2 Antibody & Isoform B validated for use in western blotting. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the N-terminus of human MeCP2. 表位 N-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes isoform B of MeCP2, but does not recognize isoform A. Additionally, this antibody recognizes the N-terminus of isoform B. 品种反应性 Human Species Reactivity Note Demonstrated to react with Human. Predicted to react with Mouse and Rabbit based on 100% sequence homology. Other homologies: Rat (94% sequence homology). 抗体类型 Polyclonal Antibody Entrez基因编号 -
">NP_001104262
基因符号 - MECP2
纯化方法 Affinity purified UniProt编号 - P51608-2
产品使用声明 质量保证 Evaluated by Western Blotting in MCF7 cell lysate.
Western Blotting Analysis: 2.0 µg/mL of this antibody detected MeCP2 in 10 µg of MCF7 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 200 µg
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