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品种反应性 主要应用 宿主 格式 抗体类型 M, H WB Rb Purified Polyclonal Antibody 描述 产品目录编号 07-531 品牌系列 Upstate
商名 - Upstate
描述 Anti-PIR121-1/Sra-1 Antibody 产品信息 格式 Purified 应用 应用 Anti-PIR121-1/Sra-1 Antibody is an antibody against PIR121-1/Sra-1 for use in IP & WB. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated, synthetic peptide corresponding to amino acids 872-886 (SQEFQRDKQPNAQPQ-C) of human PIR121-1/Sra-1, with a C-terminal cysteine added for conjugation purposes. 宿主 Rabbit 特异性 PIR121-1/Sra-1 (aka CYFIP1) 同种型 IgG 品种反应性 MouseHuman 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_014608
基因符号 - PIR121
- CYFIP2
- KIAA1168
纯化方法 Protein A purfied UniProt编号 - Q96F07
UniProt汇总 FUNCTION: SwissProt: Q96F07 # Involved in T-cell adhesion and p53-dependent induction of apoptosis. Does not bind RNA.
SIZE: 1278 amino acids; 148399 Da
SUBUNIT: Interacts with FMR1, FXR1 AND FXR2. Component of the WAVE1 complex composed of ABI2, CYFIP2, C3orf10/HSPC300, NCKAP1 and WASF1/WAVE1. CYFIP2 binds to activated RAC1 which causes the complex to dissociate, releasing activated WASF1. The complex can also be activated by NCK1.
SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm, perinuclear region. Cell junction, synapse, synaptosome. Note=Highly expressed in the perinuclear region. Enriched in synaptosomes. Treatment with leptomycin-B triggers translocation to the nucleus.
DISEASE:SwissProt: Q96F07 # Up-regulated significantly in CD4+ T lymphocytes from patients with multiple sclerosis (at protein level).
SIMILARITY: SwissProt: Q96F07 ## Belongs to the CYFIP family.产品使用声明 质量保证 routinely evaluated by immunoblot on RIPA homogenates from rat brain 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 stable 2 years at -20°C from date of shipment 包装信息 数量 200 µg
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