merck millipore,默克密理博,116818,Adenosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-Bromo-, Sp-Isomer, Sodium Salt

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Merck Millipore 默克密理愽

merck millipore,默克密理博,116818,Adenosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-Bromo-, Sp-Isomer, Sodium Salt - Calbiochem

经验配方
C₁₀H₁₀BrN₅O₅PS · Na

描述
概述	A potent cell-permeable, metabolically-stable activator of cAMP-dependent protein kinase (PKA). Induces guanine nucleotide exchange factor activity of GEFI (also known as Epac) and GEFII towards Rap1 both in vivo and in vitro. Significantly more lipophilic and cell-permeable than Sp-cAMPS (Cat. No. 116815). Note: 5 µmol = 2.23 mg.
产品目录编号	116818
品牌系列	Calbiochem®
同义词	Sp-8-Br-cAMPS, Na

参考
参考	Kawasaki, H., et al. 1998. Science 282, 2275. de Rooij, J., et al. 1998. Nature 396, 474. Holen, I., et al. 1996. Eur. J. Biochem. 236, 163. Schaap, P., et al. 1993. J. Biol. Chem. 268, 6323. Yokozaki, H., et al. 1992. Cancer Res. 52, 2504.

产品信息
具有ATP竞争性	N
声明	Sold under license of Patent DE 3,802,865.4 issued to BIOLOG LSI.
形式	Lyophilized
Hill配方	C₁₀H₁₀BrN₅O₅PS · Na
化学配方	C₁₀H₁₀BrN₅O₅PS · Na
Molar Mass	446.1
吸湿	Hygroscopic
可逆	N
结构配方图像

生物信息
主靶	PKA
纯度	≥99% by HPLC

理化信息
细胞可渗透	Y
溶解度	H₂O

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Standard Handling
储存	-20°C
吸湿	Hygroscopic
无需冷冻	No
特殊指南	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

merck millipore,默克密理博,116818,Adenosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-Bromo-, Sp-Isomer, Sodium Salt - Calbiochem

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