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品种反应性 主要应用 宿主 格式 抗体类型 M, H WB, IHC Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABE281 Replaces 04-1047 描述 Anti-EZH1 Antibody Alternate Names - Enhancer of zeste homolog 1
- Histone-lysine N-methyltransferase EZH1
- ENX-2
背景信息 Polycomb protein group complexes are responsible for the regulation of hundreds of genes in mammals and insects. These proteins are responsible for the assembly and packaging of chromatin and for the induction of methylation on Histone H3. EZH1 is the catalytic subunit of the PRC2/EED-EZH1 complex. This complex methylates Lys-27 of histone H3, which leads to transcriptional repression of the affected target gene. EZH1 is required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in maintaining the identity of embryonic stem cells. 产品信息 格式 Affinity Purified 控制 - Mouse embryonic stem cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect the EZH1 protein using this Anti-EZH1 validated for use in IHC & WB. 主要应用 - Western Blotting
- Immunohistochemistry
应用说明 Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected EZH1 in human lung and kidney tissues. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human EZH1. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody potentially recognizes all isoforms of EZH1. 品种反应性 MouseHuman Species Reactivity Note Demonstrated to react with Human, and Mouse. Predicted to react with Rat, Rhesus Macaque, and Bovine based on 100% sequence homology. Other homologies: Porcine (94% sequence homology). 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_001982
基因符号 - KIAA0388
- EZH1
纯化方法 Affinity purified UniProt编号 - Q92800
产品使用声明 质量保证 Evaluated by Western Blot in mouse embryonic stem cell lysate.
Western Blot Analysis: 0.2 µg/mL of this antibody detected EZH1 in 10 µg of mouse embryonic stem cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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