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品种反应性 主要应用 宿主 格式 抗体类型 R, M, H WB, ICC Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABE184 描述 Anti-Fox2 Antibody Alternate Names - RNA-binding protein 9
- RNA binding protein fox-1 homolog 2
- Fox-1 homolog B
- Fox-1 homolog Fxh
- Hexaribonucleotide-binding protein 2
- RNA-binding motif protein 9
背景信息 Fox2, also referred to as RNA binding protein fox-1 homolog 2, is an RNA binding protein involved in the regulation of tissue-specific alternative splicing. This protein interacts with the ER-alpha N-terminal activation domain, and contains a highly conserved RRM (RNA recognition motif), which associates with 5'-UGCAUGU-3' elements. This protein has been demonstrated to regulate alternative splicing of tissue specific exons and differentially spliced exons during erythropoiesis. 产品信息 格式 Affinity Purified 控制 - C2C12 cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Use Anti-Fox2 Antibody (Rabbit Polyclonal Antibody) validated in IHC(P), ICC, WB to detect Fox2 also known as RNA binding protein fox-1 homolog 2, Fox-1 homolog B. 主要应用 - Western Blotting
- Immunocytochemistry
应用说明 Immunohistochemistry Analysis: A 1:300 dilution from a representative lot detected Fox2 in human cerebellum tissue.
Immunocytochemistry Analysis: 1 µg/mL from a representative lot detected Fox2 in A431 cells.生物信息 免疫原品种 MBP-tagged recombinant protein corresponding to mouse Fox2. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 RatMouseHuman Species Reactivity Note Demonstrated to react with Human, Mouse, and Rat. Other homologies: Bovine (98% sequence homology), Canine (98% sequence homology), Equine (98% sequence homology). 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_444334
基因符号 - Rbm9
- Rbfox2
- Fox2
- Fxh
- Hrnbp2
纯化方法 Affinity purified UniProt编号 - Q8BP71
UniProt汇总 FUNCTION: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis. Seems to act as a coregulatory factor of ER-alpha.
SUBUNIT STRUCTURE: Interacts with ER-alpha N-terminal activation domain.
SUBCELLULAR LOCATION: Nucleus. Cytoplasm.产品使用声明 质量保证 Evaluated by Western Blot in C2C12 cell lysate.
Western Blot Analysis: 50 ng/mL of this antibody detected Fox2 in 10 µg of C2C12 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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