merck millipore,默克密理博,ABE1414,Anti-MEIOB Antibody

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
M	ICC, WB	Rb	Serum	Polyclonal Antibody

描述
产品目录编号	ABE1414
描述	Anti-MEIOB Antibody
Alternate Names	MLZ-675 Meiosis-specific with OB domain-containing protein Protein expressed in male leptotene and zygotene spermatocytes 675
背景信息	MEIOB is a single stranded binding protein required for proper homologous recombination in meiosis I. MEIOB is required for proper DNA strand repair at double strand breaks and faithful synapsis of the chromosomes. MEIOB is also required for successful completion of meiotic recombination and is part of a multiprotein complex with RPA2 and SPATA22 proteins. MEIOB is expressed in the gonads and specifically in ovary and testis starting at the 14th weeks post fertilization. MEIOB is also expressed in a variety of tumors but not in other tissues other than testis and ovary. Because of its unique expression MEIOB is being examined as a possible anti-cancer autoimmune agent.

产品信息
格式	Serum
演示	Rabbit polyclonal serum with 0.05% sodium azide.

应用
应用	This Anti-MEIOB Antibody is validated for use in Western Blotting and Immunoprecipitation and Immunocytochemistry for the detection of MEIOB.
主要应用	Immunocytochemistry Western Blotting
应用说明	Immunoprecipitation Analysis: A representative lot immunoprecipitated MEIOB in P18 testes (Luo, M., et al. (2013). Nature. DOI: 10.1038/ncomms3788 pg. 1-12). Immunocytochemistry Analysis: A representative lot detected MEIOB in mouse spermatocytes (Luo, M., et al. (2013). Nature. DOI: 10.1038/ncomms3788 pg. 1-12).

生物信息
免疫原品种	Recombinant protein corresponding to mouse MEIOB.
浓缩	Please refer to lot specific datasheet.
宿主	Rabbit
品种反应性	Mouse
Species Reactivity Note	Mouse.
抗体类型	Polyclonal Antibody
Entrez基因编号	NP_083473
基因符号	Meiob
纯化方法	Unpurified
UniProt编号	Q9D513

产品使用声明
质量保证	Evaluated by Western Blotting in mouse testis tissue lysate. Western Blotting Analysis: A 1:1,000 dilution of this antibody detected MEIOB in 10 µg of mouse testis tissue lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

包装信息
数量	100 µL

merck millipore,默克密理博,ABE1414,Anti-MEIOB Antibody

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