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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABD137 描述 Anti-ESRRB Antibody Alternate Names - Nuclear receptor subfamily 3 group B member 2
- Steroid hormone receptor ERR2
- ERR beta-2
- Estrogen receptor-like 2
- Estrogen-related receptor beta
- ERR-beta
背景信息 Steroid hormone receptor ERR2, also known as ERR beta-2 or Estrogen receptor-like 2 or Estrogen-related receptor beta (ERR-beta), and encoded by the gene name ESRRB or ERRB2 or ESRL2, was initially identified in mouse embryonic carcinoma stem cells and was found to be expressed exclusively in trophoblast progenitor cells between days 6.5 and 7.5 post coitum. Recent studies have shown that ESRRB is part of an POU5F1/Oct4-centered protein interaction network in embryonic stem (ES) cells. It is thought to interact with other ES transcription factors such as NANOG within this network, activating POU5F1 transcription and thereby sustaining self-renewal and pluripotency in ES cells. Mutations in ESRRB have been associated with autosomal recessive deafness which is a form of non-syndromic deafness characterized by non-progressive, prelingual hearing loss. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. 应用 应用 Anti-ESRRB Antibody detects level of ESRRB & has been published & validated for use in ESRRB. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated synthetic peptide corresponding to the N-terminus of human ESRRB. 表位 N-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Uniprot describes 2 isoforms produced by alternative splicing at ~56 kDa and 1 isoform at ~48 kDa. 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - NR3B2
- ESRRB
- ERRB2
- ESRL2
纯化方法 Antigen Affinity purified UniProt编号 - O95718
产品使用声明 质量保证 Evaluated by Western Blotting in Human heart tissue lysate with and without blocking peptide.
Western Blotting Analysis: 1 μg/mL of this antibody detected ESRRB in Human heart tissue lysate with and without blocking peptide.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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