merck millipore,默克密理愽
  • merck millipore,默克密理博,ABC88,Anti-FK506-binding protein-like (FKBPL) Antibody

  • merck millipore,默克密理博,ABC88,Anti-FK506-binding protein-like (FKBPL) Antibody

    产品名称：Anti-FK506-binding protein-like (FKBPL) Antibody
    产品型号：ABC88
    Detect FK506-binding protein-like (FKBPL) using this Anti-FK506-binding protein-like (FKBPL) Antibody validated for use in WB, IH(P).

    merck millipore,默克密理博,ABC88,Anti-FK506-binding protein-like (FKBPL) Antibody

  • 产品介绍
  • merck millipore,默克密理博,ABC88,Anti-FK506-binding protein-like (FKBPL) Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Rhesus Macaque, H, M, R, BWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 ABC88
    描述 Anti-FK506-binding protein-like (FKBPL) Antibody
    Alternate Names
    • WISp39
    • FK506-binding protein-like
    • WAF-1/CIP1 stabilizing protein 39
    背景信息 FK506-binding protein-like (FKBPL) belongs to the family of FK506 binding proteins and is an immunophilin-like protein that plays a role in immunoregulation and the cellular stress response. It is ubiquitously expressed with higher levels in testis. Mutations in FK506-binding protein-like have been associated with human infertility.
    产品信息
    格式 Affinity Purified
    控制
    • HeLa cell lysate
    演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Detect FK506-binding protein-like (FKBPL) using this Anti-FK506-binding protein-like (FKBPL) Antibody validated for use in WB, IH(P).
    主要应用
    • Western Blotting
    应用说明 Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected FK506-binding protein-like in human prostate amd rat testis tissues.
    生物信息
    免疫原品种 KLH-conjugated linear peptide corresponding to human FK506-binding protein-like at the TPR1 region.
    表位 TPR1 region
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 This antibody recognizes FK506-binding protein-like at the TPR1 region.
    品种反应性 Rhesus MacaqueHumanMouseRatBovine
    Species Reactivity Note Demonstrated to react with Human, Mouse, and Rat. Predicted to react with Bovine and Rhesus Macaque based on 100% sequence homology.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_071393
    Entrez基因汇总 The protein encoded by this gene has similarity to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The encoded protein is thought to have a potential role in the induced radioresistance. Also it appears to have some involvement in the control of the cell cycle. [provided by RefSeq, Jul 2008].
    基因符号
    • NG7
    • FKBPL
    • DIR1
    纯化方法 Affinity purified
    UniProt编号
    • Q9UIM3
    UniProt汇总 FUNCTION: May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.

    TISSUE SPECIFICITY: Ubiquitously expressed with higher levels in testis.

    PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.

    SEQUENCE SIMILARITIES: Contains 3 TPR repeats.

    SEQUENCE CAUTION: The sequence BAB15663.1 differs from that shown. Reason: Frameshift at positions 201, 205 and 319.

    The sequence CAG33655.1 differs from that shown. Reason: Frameshift at position 201.
    产品使用声明
    质量保证 Evaluated by Western Blot in HeLa cell lysate.

    Western Blot Analysis: 0.05 µg/mL of this antibody detected FK506-binding protein-like on 10 µg of HeLa cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,ABC88,Anti-FK506-binding protein-like (FKBPL) Antibody

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