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品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC294 描述 Anti-CDK9 Antibody Alternate Names - Tat-associated kinase complex catalytic subunit
- Cyclin-dependent kinase 9
- C-2K
- Cell division cycle 2-like protein kinase 4
- Cell division protein kinase 9
- Serine/threonine-protein kinase PITALRE
背景信息 Cyclin-dependent kinase 9 (CDK9) is a member of the protein kinase superfamily and is involved in the regulation of transcription. CDK9 is located primarily in the nucleus. The CDK9/cyclin-K complex is required for genome integrity maintenance, by promoting cell cycle recovery from replication arrest and limiting single-stranded DNA amount in response to replication stress. This reduces the breakdown of stalled replication forks and avoiding DNA damage. Mutations in CDK9 have been assoicated with cardiac myocyte enlargement leading to cardiac hypertrophy. 产品信息 格式 Affinity Purified 控制 - Human placenta tissue lysate
演示 Purified rabbit polyclonal in buffer containing PBS with 0.1% sodium azide and 50% glycerol. 应用 应用 Anti-CDK9 detects levels of CDK9 proteins & has been published & validated for use in WB & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected CDK9 in glioma tissue. 生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human CDK9. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 同种型 IgG 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - TAK
- CDK9
- CDC2L4
纯化方法 Antigen Affinity purified UniProt编号 - P50750
产品使用声明 质量保证 Evaluated by Western Blotting in human placenta tissue lysate.
Western Blotting Analysis: A 1:1,200 dilution of this antibody detected CDK9 in 30 µg of human placenta tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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