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品种反应性 主要应用 宿主 格式 抗体类型 R, H, M IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC273 描述 Anti-SLC22A18 Antibody Alternate Names - p45-Beckwith-Wiedemann region 1 A
- Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene A protein
- Efflux transporter-like protein
- Imprinted multi-membrane-spanning polyspecific transporter-related protein 1
- Organic cation transporter-like protein 2
- Solute carrier family 22 member 1-like
- Tumor-suppressing STF cDNA 5 protein
- Tumor-suppressing subchromosomal transferable fragment candidate gene 5 protein
背景信息 SLC22A18 is a member of the family of polyspecific organic-cation transporters that localize at the apical membrane surface of renal proximal tubules. SLC22A18 is expressed at high levels in the kidney, liver, colon and in fetal renal proximal tubules and present at lower levels in heart, brain and lung. Defects in SLC22A18 are associated with breast and lung cancer and are the cause of rhabdomyosarcoma type 1, a malignant tumor derived from striated muscle. More recently, SLC22A18 has been shown to function as a tumor suppressor in glioma and represents a candidate biomarker for long-term survival in this disease. 产品信息 格式 Affinity Purified 控制 - Mouse brain tissue lysate
演示 Purified rabbit polyclonal in buffer containing PBS with 0.1% sodium azide and 50% glycerol. 应用 应用 This SLC22A18 antibody is validated for use in WB & IHC for the detection of the SLC22A18 protein. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Western Blotting Analysis: A 1:500 dilution from a representative lot detected SLC22A18 in 10 µg of rat brain tissue lysate.
Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected SLC22A18 in human liver and colon cancer tissues.生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human SLC22A18. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 RatHumanMouse Species Reactivity Note Demonstrated to react with Human, Mouse, and Rat. 抗体类型 Polyclonal Antibody 基因符号 - TSSC5
- SLC22A18
- BWR1A
- BWSCR1A
- HET
- IMPT1
- ITM
- ORCTL2
- SLC22A1L
纯化方法 Antigen Affinity purified UniProt编号 - Q96BI1
产品使用声明 质量保证 Evaluated by Western Blotting in mouse brain tissue lysate.
Western Blotting Analysis: A 1:500 dilution of this antibody detected SLC22A18 in 10 µg of mouse brain tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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