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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC110 描述 Anti-ELMO1 Antibody Alternate Names - Protein ced-12 homolog
- Engulfment and cell motility protein 1
背景信息 Engulfment and cell motility protein 1 (ELMO1) is a cytoplasmic protein involved in the clearance of apoptotic cells by phagocytosis. ELMO1 is activated downstream of the phosphatidylserine receptor BAI1. ELMO1 binds to DOCK180 and facilitates its transport to the plasma membrane where DOCK180 activates the GTPase RAC1, possibly via Arf6. RAC1, like other small GTPases, mediate cytoskeleton remodeling and cell motility which is necessary for the internalization of target cells. 产品信息 格式 Affinity Purified 控制 - Jurkat cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect ELMO1 using this Anti-ELMO1 Antibody validated for use in Western Blotting. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human ELMO1 at the ELMO domain. 表位 ELMO domain 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes ELMO1 at the ELMO domain. 品种反应性 Human Species Reactivity Note Demonstrated to react with Human. Predicted to react with Mouse, Bovine, and Rhesus Macaque based on 100% sequence homology. No homology to Rat was found. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_055615
基因符号 - ELMO1
纯化方法 Affinity purified UniProt编号 - Q92556
产品使用声明 质量保证 Evaluated by Western Blot in Jurkat cell lysate.
Western Blot Analysis: 0.1 µg/mL of this antibody detected ELMO1 on 10 µg of Jurkat cell lysate.
使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 50 µg
上一件merck millipore产品：merck millipore,默克密理博,PFHYS1008,Millicell HY 5-layer cell culture flask, T-1000, sterile
下一件merck millipore产品：merck millipore,默克密理博,SCM014,Neural Stem Cell Freezing Medium (1X)
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