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品种反应性 主要应用 宿主 格式 抗体类型 R WB, IHC Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB9830-200UL 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-K2P4.1 Antibody Alternate Names - TRAAK, TWIK-related arachidonic acid-stimulated K<sup>+</sup> channel, KCNK4
- TRAAK
- TWIK-related arachidonic acid-stimulated K<sup>+</sup> channel
产品信息 格式 Affinity Purified 控制 - Included free of charge with the antibody is 40 μg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 μL of sterile deionized water. For negative control, preincubate 1 μg of peptide with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.
演示 Affinity purified immunoglobulin. Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.025% sodium azide as a preservative. Reconstitute with 200 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min). 应用 应用 This Anti-K2P4.1 Antibody is validated for use in IH, WB for the detection of K2P4.1. 主要应用 - Western Blotting
- Immunohistochemistry
应用说明 Western blot: 1:200 using ECL on rat cerebellum lysate and HEK- K2P4.1 transfected cells.
Immunohistochemistry on rat brain sections.
Dilutions should be made using a carrier protein such as BSA (1-3%).
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Purified peptide from amino acids 343-359 of human K2P4.1 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes K2P4.1 (TRAAK, TWIK-related arachidonic acid-stimulated K+ channel, KCNK4). 同种型 IgG 品种反应性 Rat Species Reactivity Note The immunogen sequence is identical in mouse, rat and canine. 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_033310.2
Entrez基因汇总 Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The encoded protein homodimerizes and functions as an outwardly rectifying channel. It is expressed primarily in neural tissues and is stimulated by membrane stretch and polyunsaturated fatty acids. 基因符号 - TRAAK1
- KCNK4
- TRAAK
- K2p4.1
纯化方法 Immunoaffinity purified UniProt编号 - Q9NYG8
UniProt汇总 FUNCTION: SwissProt: Q9NYG8 # Voltage insensitive, instantaneous, outwardly rectifying potassium channel. Outward rectification is reversed at high external K(+) concentrations (By similarity).
SIZE: 393 amino acids; 42704 Da
SUBUNIT: Homodimer (Potential).
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential).
SIMILARITY: SwissProt: Q9NYG8 ## Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. 包装信息 数量 200 µL
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