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merck millipore,默克密理博,AB9624,Anti-Ephrin B phosphoTyr298 Antibody
产品名称：Anti-Ephrin B phosphoTyr298 Antibody
产品型号：AB9624
Anti-Ephrin B phosphoTyr298 Antibody detects level of Ephrin B phosphoTyr298 & has been published & validated for use in WB.
merck millipore,默克密理博,AB9624,Anti-Ephrin B phosphoTyr298 Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB9624 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Ephrin B phosphoTyr298 Antibody 产品信息 格式 Affinity Purified 演示 Affinity purified immunoglobulin. Liquid in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50% glycerol. 应用 应用 Anti-Ephrin B phosphoTyr298 Antibody detects level of Ephrin B phosphoTyr298 & has been published & validated for use in WB. 主要应用 - Western Blotting
应用说明 Western blot: 1:1,000. This antibody detects a strong band around 46kDa in rat testes lysate.
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Synthetic peptide of amino acids surrounding the phosphoTyrosine 298 site of Xenopus EphrinB. Xenopus Tyrosine 298 is the homolog of mouse, rat and human Tyrosine 317 and chicken Tyrosine 305. 宿主 Rabbit 特异性 EphrinB, phosphoTyrosine 298. The antibody recognizes a protein of ~46 kDa corresponding to EphrinB, phosphoTyrosine 298 in lysates from rat testes. Immunolabeling is blocked by l-phosphatase treatment. 品种反应性 Rat 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_004441.3
Entrez基因汇总 Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members. 基因符号 - EC 2.7.10.1
- EPHB1
- NET
- Elk
- FLJ37986
- Hek6
- ELK
- EPHT2
- EphB1
- HEK6
修改 - Phosphorylation
UniProt编号 - P54762
UniProt汇总 FUNCTION: SwissProt: P54762 # Receptor for members of the ephrin-B family. Binds to ephrin-B1, -B2 and -B3. May be involved in cell-cell interactions in the nervous system.
SIZE: 984 amino acids; 109885 Da
SUBUNIT: The ligand-activated form interacts with GRB2, GRB10 and NCK through their respective SH2 domains. The GRB10 SH2 domain binds EPHB1 through Tyr-928, while GRB2 binds residues within the catalytic domain. The NCK SH2 domain binds EPHB1 through Tyr-594. Interacts with PRKCABP (By similarity).
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
TISSUE SPECIFICITY: Preferentially expressed in brain.
SIMILARITY: SwissProt: P54762 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. & Contains 2 fibronectin type-III domains. & Contains 1 protein kinase domain. & Contains 1 SAM (sterile alpha motif) domain.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self defrosting freezer. 包装信息 数量 100 µL
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