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  • merck millipore,默克密理博,AB907,Anti-Desmin Antibody

  • merck millipore,默克密理博,AB907,Anti-Desmin Antibody

    产品名称：Anti-Desmin Antibody
    产品型号：AB907
    Anti-Desmin Antibody is an antibody against Desmin for use in WB, IH(P).

    merck millipore,默克密理博,AB907,Anti-Desmin Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB907,Anti-Desmin Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    M, B, Ch, HWBRbSerumPolyclonal Antibody
    描述
    产品目录编号 AB907
    Replaces 04-585
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Desmin Antibody
    产品信息
    格式 Serum
    演示 Rabbit antiserum. Liquid containing 0.1% sodium azide as a preservative.
    应用
    应用 Anti-Desmin Antibody is an antibody against Desmin for use in WB, IH(P).
    主要应用
    • Western Blotting
    应用说明 Indirect immunofluorescence of formalin fixed paraffin-embedded sections of human intestine sections: 1:10-1:20.

    Immunoblotting

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Purified desmin from chicken gizzard, isolated by modified procedure of Geisler, et al [J. Biol Chem. (1980). 111:425-433].
    宿主 Rabbit
    特异性 Desmin. Reacts specifically with desmin in cultured cells or tissue preparations originating from chicken, human, bovine and mouse tissue. AB907 specifically stains the wide desmin band in immunoblot at a molecular weight of 50-55 kD.
    品种反应性 MouseBovineChickenHuman
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_001927.3
    Entrez基因汇总 This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
    基因符号
    • desmin
    • DES
    • CSM2
    • FLJ41013
    • FLJ39719
    • CSM1
    • FLJ41793
    • FLJ12025
    • Desmin.
    • CMD1I
    UniProt编号
    • P17661
    UniProt汇总 FUNCTION: SwissProt: P17661 # Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures.
    SIZE: 470 amino acids; 53536 Da
    SUBUNIT: Homopolymer.
    SUBCELLULAR LOCATION: Cytoplasm.
    DISEASE: SwissProt: P17661 # Defects in DES are the cause of desmin-related cardio- skeletal myopathy (CSM) [MIM:601419]; also known as desmin-related myopathy (DRM). CSM is characterized by skeletal muscle weakness associated with cardiac conduction blocks, arrhythmias, restrictive heart failure, and by intracytoplasmic accumulation of desmin-reactive deposits in cardiac and skeletal muscle cells. A desmin-related myopathy can have a distal onset, it is then known as hereditary distal myopathy (HDM). & Defects in DES are the cause of dilated cardiomyopathy 1I (CMD1I) [MIM:604765]. CMD1I is an autosomal form of dilated cardiomyopathy characterized by ventricular dilatation and impaired systolic function.
    SIMILARITY: SwissProt: P17661 ## Belongs to the intermediate filament family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 500 µL

    merck millipore,默克密理博,AB907,Anti-Desmin Antibody

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