merck millipore,默克密理愽
  • merck millipore,默克密理博,AB5860-200UL,Anti-Potassium Channel TREK-1 Antibody

  • merck millipore,默克密理博,AB5860-200UL,Anti-Potassium Channel TREK-1 Antibody

    产品名称：Anti-Potassium Channel TREK-1 Antibody
    产品型号：AB5860-200UL
    Detect Potassium Channel TREK-1 using this Anti-Potassium Channel TREK-1 Antibody validated for use in WB.

    merck millipore,默克密理博,AB5860-200UL,Anti-Potassium Channel TREK-1 Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB5860-200UL,Anti-Potassium Channel TREK-1 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, HWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB5860-200UL
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Potassium Channel TREK-1 Antibody
    Alternate Names
    • Kcnk2
    • Twik-Related K+ Channel 1
    产品信息
    格式 Affinity Purified
    控制
    • CONTROL ANTIGEN: Included free of charge with the antibody is 40 μg of control antigen. The stock solution of the antigen can be made up using 100 μL of sterile distilled water. For negative control, preincubate 1 μg of peptide with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.
    演示 Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.025% sodium azide as a preservative. Reconstitute with 200 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min.)
    应用
    应用 Detect Potassium Channel TREK-1 using this Anti-Potassium Channel TREK-1 Antibody validated for use in WB.
    主要应用
    • Western Blotting
    应用说明 Western blot: 1:200 using ECL on rat brain membranes.

    Dilutions should be made using a carrier protein such as BSA (1-3%)

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Synthetic peptide corresponding amino acids 8-28 of human TREK-1 (Accession numbers AAF89743, AAD47569).
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes TREK-1 (Twik-Related K+ Channel 1, Kcnk2). The epitope does not share homology with any other known proteins.
    品种反应性 RatHuman
    Species Reactivity Note It is expected that the antibody will also react with mouse due to sequence homology (17/18). Other species have not been tested.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_014217.3
    • NM_001017424.2
    • NM_001017425.2
    Entrez基因汇总 This gene encodes one of the members of the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium out of the cell to control resting membrane potential. The channel can be opened, however, by certain anesthetics, membrane stretching, intracellular acidosis, and heat. Three transcript variants encoding different isoforms have been found for this gene.
    基因符号
    • K2p2.1
    • KCNK2
    • hTREK-1e
    • MGC126742
    • hTREK-1c
    • TREK
    • TPKC1
    • MGC126744
    • TREK1
    • TREK-1
    UniProt编号
    • O95069
    UniProt汇总 FUNCTION: SwissProt: O95069 # Outward rectifying potassium channel.
    SIZE: 426 amino acids; 47093 Da
    SUBUNIT: Homodimer (Potential).
    SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential).
    SIMILARITY: SwissProt: O95069 ## Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
    MISCELLANEOUS: Activated by volatile general anesthetics such as chloroform, halothane and isoflurane.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain lyophilized material at -20°C for up to 12 months. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 200 µL

    merck millipore,默克密理博,AB5860-200UL,Anti-Potassium Channel TREK-1 Antibody

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