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品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB Rb Purified Polyclonal Antibody 描述 产品目录编号 07-121 品牌系列 Upstate
商名 - Upstate
描述 Anti-Moesin Antibody 产品信息 格式 Purified 演示 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, and 0.05% sodium azide. 应用 应用 This Anti-Moesin Antibody is validated for use in WB for the detection of Moesin. 主要应用 - Western Blotting
生物信息 免疫原品种 peptide corresponding to amino acids 401-413 of human Moesin (C-EALLQASRDQKKT) 宿主 Rabbit 特异性 Moesin 同种型 IgG 品种反应性 RatHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_002444
Entrez基因汇总 Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. 基因符号 - moesin
- MSN
- Moesin
纯化方法 Protein A chromatography UniProt编号 - P26038
UniProt汇总 FUNCTION: SwissProt: P26038 # Probably involved in connections of major cytoskeletal structures to the plasma membrane.
SIZE: 577 amino acids; 67820 Da
SUBUNIT: In resting T-cells, part of a PAG1-SLC9A3R1-MSN complex which is disrupted upon TCR activation (By similarity). Binds SLC9A3R1.
SUBCELLULAR LOCATION: Cytoplasm (By similarity). Note=Phosphorylated form is enriched in microvilli-like structures at apical membrane (By similarity).
TISSUE SPECIFICITY: In all tissues and cultured cells studied.
PTM: Phosphorylation on Thr-558 is crucial for the formation of microvilli-like structures (By similarity).
SIMILARITY: SwissProt: P26038 ## Contains 1 FERM domain.产品使用声明 质量保证 routinely evaluated by immunoblot on HeLa, A431, Jurkat, HFF, Raji, 3T3, CTLL, L6 or PC-12 cell lysates 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 200 µg
上一件merck millipore产品：merck millipore,默克密理博,14-587,p38α/SAPK2a (6His-tag) Protein, active, 10 µg
下一件merck millipore产品：merck millipore,默克密理博,189738,Streptavidin, TEXAS RED Conjugate
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