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品种反应性 主要应用 宿主 格式 抗体类型 M WB Rb Serum Polyclonal Antibody 描述 产品目录编号 AB5691 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Nucleostemin Antibody 背景信息 Nucleostemin is a protein found in the nucleoli of embryonic stem cells, adult CNS stem cells, primitive cells in the bone marrow and cancer cells. It is not in the differentiated cells of most adult tissues. It has been suggested to play a role in controlling the cell-cycle progression in stem cells and cancer cells. 产品信息 格式 Serum 控制 - MBL-5 cell lysate, E14tG2a (Mouse embryonic stem cell line) whole cell lysate
演示 Rabbit serum. Liquid. 应用 应用 Anti-Nucleostemin Antibody is an antibody against Nucleostemin for use in WB. 主要应用 - Western Blotting
应用说明 Western blot: 1:5,000-1:10,000 using ECL. The antibody reacts with a protein of ~ 63 kDa on MBL-5 cell lysate.
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Synthetic peptide from mouse nucleostemin. 宿主 Rabbit 特异性 Nucleostemin, mouse. 品种反应性 Mouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_206826.1
- NM_014366.4
- NM_206825.1
基因符号 - NNP47
- GNL3
- C77032
- NS
- MGC800
- E2IG3
- nucleostemin
- Nucleostemin
UniProt编号 - Q9BVP2
UniProt汇总 FUNCTION: SwissProt: Q9BVP2 # May be required to maintain the proliferative capacity of stem cells.
SIZE: 549 amino acids; 61997 Da
SUBUNIT: May interact with p53/TP53 via its basic domain (By similarity).
SUBCELLULAR LOCATION: Nucleus (By similarity). Nucleus, nucleolus (By similarity). Note=Shuttles between the nucleus and nucleolus (By similarity).
DOMAIN: SwissProt: Q9BVP2 The basic domain (B) allows nucleolar localization in the absence of GTP. The intermediate domain (I) inhibits nucleolar localization by the B domain and is required for exit from the nucleolus. Exit from the nucleolus to the nucleoplasm requires both the I and the acidic (A) domains, and may be triggered by GTP hydrolysis (By similarity).
SIMILARITY: Belongs to the MMR1/HSR1 GTP-binding protein family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 50 µL
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