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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, R, H, Zebrafish IHC, ICC Rb Serum Polyclonal Antibody 描述 产品目录编号 AB5475 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Prox 1 Antibody 背景信息 Prox1, the homolog of Drosophila Prospero, is a homeobox-containing transcription factor that binds and functions as a co-receptor of liver receptor homolog 1 (LRH1/NR5A2). It is a specific marker for lymphatic endothelial cells, as well as hepatoblasts and hepatocytes. Human Prox1 shares 97% amino acid sequence identity with mouse and rat Prox1. 产品信息 格式 Serum 控制 - Embryonic brain tissue.
演示 Rabbit serum in 50 % glycerol. 应用 应用 Detect Prox 1 using this Anti-Prox 1 Antibody validated for use in IC, IH. 主要应用 - Immunohistochemistry
- Immunocytochemistry
应用说明 Immunohistochemistry:
1:2,000-1:10,000 with overnight incubation on 4% paraformaldehyde fixed, frozen tissue sections. For embryos immersion fixation is recommended. For older animals perfusion fixation is recommended. Suggested permeabilization solution is 0.1% Triton X100. Suggested blocking buffer is PBS with 0.1% Triton and 10% serum.
Immunocytochemistry:
A previous lot of this antibody was used on Immunocytochemistry生物信息 免疫原品种 Synthetic peptide from the C-terminus of mouse Prox1. 表位 C-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes Prox1. The antibody is useful for identifying Prox1 expressing cells during the development of many areas of the nervous system including the dorsal spinal cord, ganglionic eminences, thalamus and hippocampus. 品种反应性 MouseRatHumanZebrafish Species Reactivity Note Rat, mouse and zebrafish. The antibody is also expected to react with human. Other species have not been tested. 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_002763.3
基因符号 - PROX1
纯化方法 Unpurified UniProt编号 - Q92786
UniProt汇总 FUNCTION: SwissProt: Q92786 # May play a fundamental role in early development of CNS. May regulate gene expression and development of postmitotic undifferentiated young neurons (By similarity).
SIZE: 737 amino acids; 83203 Da
SUBCELLULAR LOCATION: Nucleus (Probable).
TISSUE SPECIFICITY: Most actively expressed in the developing lens. Detected also in embryonic brain, lung, liver and kidney. In adult, it is more abundant in heart and liver than in brain, skeletal muscle, kidney and pancreas.
SIMILARITY: SwissProt: Q92786 ## Belongs to the Prospero homeobox family. & Contains 1 Prospero-type homeobox DNA-binding domain.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage. 包装信息 数量 100 µL
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下一件merck millipore产品：merck millipore,默克密理博,MABN509,Anti-CADM4 Antibody, clone N244/5
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