merck millipore,默克密理愽
  • merck millipore,默克密理博,AB5469,Anti-Ductin Antibody

  • merck millipore,默克密理博,AB5469,Anti-Ductin Antibody

    产品名称：Anti-Ductin Antibody
    产品型号：AB5469
    Anti-Ductin Antibody detects level of Ductin & has been published & validated for use in IC, IH & WB.

    merck millipore,默克密理博,AB5469,Anti-Ductin Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB5469,Anti-Ductin Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Vrt, InvWB, ICC, IHCRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB5469
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Ductin Antibody
    产品信息
    格式 Affinity Purified
    演示 Affinity purified. Liquid in 50% glycerol. Contains no preservative.
    应用
    应用 Anti-Ductin Antibody detects level of Ductin & has been published & validated for use in IC, IH & WB.
    主要应用
    • Western Blotting
    • Immunocytochemistry
    • Immunohistochemistry
    应用说明 Western Blot: 1:500-1:1,000.

    Immunocytochemistry: 1:500

    Immunohistochemistry: 1:500

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Synthetic peptide (100% conserved in all species) cooresponding to amino acids 115 to 126 of human ATP6VOC {gb AAH07389.1}.
    宿主 Rabbit
    特异性 Recognizes ductin (the 16 kDa or c' subunit of the V-ATPase).

    SPECIES REACTIVITY:

    The immunogen sequence is common to all species (plants to man). The antibody has specifically been tested on flatworm (invertebrate) and frog and chicken embryonic tissues (vertebrate) tissue.
    品种反应性 VertebratesInvertebrates
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_001694.2
    Entrez基因汇总 This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is part of the V0 domain. This gene had the previous symbols of ATP6C and ATP6L.
    基因符号
    • EC 3.6.3.14
    • ATP6V0C
    • VATL
    • Vma3
    • ATPL
    • ATP6C
    • ATP6L
    UniProt编号
    • P27449
    UniProt汇总 FUNCTION: SwissProt: P27449 # Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
    SIZE: 155 amino acids; 15736 Da
    SUBUNIT: V-ATPase is an heteromultimeric enzyme composed of a peripheral catalytic V1 complex (main components: subunits A, B, C, D, E, and F) attached to an integral membrane V0 proton pore complex (main component: the proteolipid protein; which is present as a hexamer that forms the proton-conducting pore). Interacts with LASS2. Interacts with HTLV-1 accessory protein p12I.
    SUBCELLULAR LOCATION: Vacuole membrane; Multi-pass membrane protein.
    SIMILARITY: SwissProt: P27449 ## Belongs to the V-ATPase proteolipid subunit family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,AB5469,Anti-Ductin Antibody

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