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经验配方 CAS号 C₃₈H₃₆N₄O₄ 213416-70-7 描述 概述 A perylene-based ligand that potently inhibits human telomerase by binding to G-quadruplex DNA. The strongest binding site for PIPER appears to be the 3′-boundary of the G-quadruplex. Can also bind non-specifically to nucleic acids. May also be useful as an antiproliferative agent. 产品目录编号 528120 品牌系列 Calbiochem®
同义词 N,Nʹ-bis[2-(1-Piperidino)ethyl]-3,4,9,10-perylenetetracarboxylic Diimide, Telomerase Inhibitor IV 参考 参考 Han, H., et al. 1999. Biochemistry 38, 6981.
Fedoroff, O.Y., et al. 1998. Biochemistry 37, 12367.产品信息 CAS号 213416-70-7 具有ATP竞争性 N 形式 Dark purple solid Hill配方 C₃₈H₃₆N₄O₄ 化学配方 C₃₈H₃₆N₄O₄ Molar Mass 612.7 可逆 N 结构配方图像 生物信息 主靶 human telomerase 纯度 ≥95% by HPLC 理化信息 细胞可渗透 N 溶解度 5% Acetic acid 安全信息 R相 R: 20/21/22-40-68
Harmful by inhalation, in contact with skin and if swallowed.
Limited evidence of a carcinogenic effect.
Possible risks of irreversible effects.S相 S: 22-36
Do not breathe dust.
Wear suitable protective clothing.储存和货运信息 货运代码 Ambient Temperature Only
毒性 Harmful & Carcinogenic / Teratogenic
储存 -20°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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