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品种反应性 主要应用 宿主 格式 抗体类型 R WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB5330-200UL 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Syntaxin 4 Antibody 产品信息 格式 Affinity Purified 控制 - CONTROL ANTIGEN: Included free of charge with the antibody is 40 μg of control antigen (lyophilized powder). Reconstitute with 100 μL of sterile distilled water. For negative control, preincubate 1 μg of purified peptide with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.
演示 Affinity purified immunoglobulin. Lyophilized from PBS, pH 7.4, containing 1% BSA and 0.025% sodium azide. Reconstitute with 200 μL of sterile distilled water. Centrifuge antibody preparation before use (10,000 x g for 5 min). 应用 应用 This Anti-Syntaxin 4 Antibody is validated for use in WB for the detection of Syntaxin 4. 主要应用 - Western Blotting
应用说明 Western blotting: 0.5-1.0 μg/mL (1:200-1:500) Dilutions should be made using a carrier protein such as BSA (1-3%).
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Highly purified corresponding to residues 2-23 of rat or mouse Syntaxin 4 (Accession Q08850). 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes Syntaxin 4. 品种反应性 Rat 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_004604.3
基因符号 - Syntaxin-4
- STX4
- p35-2
- STX4A
UniProt编号 - Q12846
UniProt汇总 FUNCTION: SwissProt: Q12846 # Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones.
SIZE: 297 amino acids; 34180 Da
SUBUNIT: Binds STXBP3 and STXBP6. Binding to STXBP3 excludes binding with SNAP25. Interacts with SNAP23 and SNAP25BP. Found in a complex with VAMP8 and SNAP23 in pancreas (By similarity). Interacts with VAMP2 and STXBP4 (By similarity). Detected in a complex with SNAP23 and STXBP4. Interaction with STXBP4 excludes interaction with VAMP2 (By similarity). Interacts with STX4A (By similarity).
SUBCELLULAR LOCATION: Membrane; Single-pass type IV membrane protein (Potential).
SIMILARITY: SwissProt: Q12846 ## Belongs to the syntaxin family. & Contains 1 t-SNARE coiled-coil homology domain.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain lyophilized material at -20°C for up to 6 months. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. 包装信息 数量 200 µL
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