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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB4098 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Cathepsin S Antibody 背景信息 Cathepsin S is a lysosomal cysteine protease expressed in numerous tissues. Pro-Cathepsin S (37kDa) is processed to the active form (28 kDa single chain). It is reportedly involved in antigen presentation, general protein catabolism, and tumor progression. Because of its redistribution or increased levels in human and animal tumors, cathepsin S may have a role in invasion and metastasis. 产品信息 格式 Affinity Purified 控制 - Western blot positive control: PC-3 cell line
演示 Liquid in 0.02M Phosphate Buffer, 0.25M NaCl, with 0.1% sodium azide. 应用 应用 This Anti-Cathepsin S Antibody is validated for use in WB for the detection of Cathepsin S. 主要应用 - Western Blotting
生物信息 免疫原品种 Synthetic peptide corresponding to amino acid residues 229-246 of human Cathepsin S. 宿主 Rabbit 特异性 Recognizes mature human Cathepsin S. This antibody detects a band of approximately 30 kDa corresponding to the single chain proteolyitc product in Western blot analysis of PC-3 cell lysate. Does show some non-specific cross reactivity at 50 kDa and higher. 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_004079.3
Entrez基因汇总 The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The encoded protein can function as an elastase over a broad pH range in alveolar macrophages. Transcript variants utilizing alternative polyadenylation signals exist for this gene. 基因符号 - EC 3.4.22.27
- CTSS
- MGC3886
UniProt编号 - P25774
UniProt汇总 FUNCTION: SwissProt: P25774 # Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond- specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
SIZE: 331 amino acids; 37496 Da
SUBUNIT: Monomer.
SUBCELLULAR LOCATION: Lysosome.
SIMILARITY: SwissProt: P25774 ## Belongs to the peptidase C1 family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at 2-8°C for up to 12 months from date of receipt. 包装信息 数量 50 µg
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