• merck millipore,默克密理博,AB3794,Anti-Paxillin Antibody
  • merck millipore,默克密理博,AB3794,Anti-Paxillin Antibody

    产品名称:Anti-Paxillin Antibody
    产品型号:AB3794
    Detect Paxillin using this Anti-Paxillin Antibody validated for use in IP, WB, IH.

    merck millipore,默克密理博,AB3794,Anti-Paxillin Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB3794,Anti-Paxillin Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Rb, H, M, RIHC, WBRbPurifiedPolyclonal Antibody
    描述
    产品目录编号 AB3794
    Replaces 04-581
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Paxillin Antibody
    产品信息
    格式 Purified
    演示 Purified immunoglobulin. Liquid in PBS with 50% Glycerol and 0.01% sodium azide, pH 7.3.
    应用
    应用 Detect Paxillin using this Anti-Paxillin Antibody validated for use in IP, WB, IH.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Western blot: 1:1,000 on mouse brain lysates.
    Immunohistochemistry: 1:10.
    Immunoprecipitation: 5 μL/mL lysate

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Recombinant human paxillin.
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Paxillin
    品种反应性 RabbitHumanMouseRat
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_002859.1
    基因符号
    • FLJ16691
    • PXN
    • Paxillin.
    • paxillin
    UniProt编号
    • P49023
    UniProt汇总 FUNCTION: SwissProt: P49023 # Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
    SIZE: 591 amino acids; 64533 Da
    SUBUNIT: Binds in vitro to vinculin as well as to the SH3 domain of c-SRC and, when tyrosine phosphorylated, to the SH2 domain of V-CRK. Isoform beta binds to focal adhesion kinase but weakly to vinculin. Isoform gamma binds to vinculin but only weakly to focal adhesion kinase. Interacts with GIT1, NUDT16L1/SDOS, PARVA and TGFB1I1. Component of cytoplasmic complexes, which also contain GIT1, ARHGEF6 and PAK1 (By similarity). Binds DDEF2. Interacts with unphosphorylated ITGA4. Interacts with RNF5.
    PTM: Phosphorylated on tyrosine residues during integrin-mediated cell adhesion, embryonic development, fibroblast transformation and following stimulation of cells by mitogens.
    SIMILARITY: SwissProt: P49023 ## Belongs to the paxillin family. & Contains 4 LIM zinc-binding domains.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted for up to 6 months from date of receipt. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 50 µL

    merck millipore,默克密理博,AB3794,Anti-Paxillin Antibody

上一件merck millipore产品:merck millipore,默克密理博,HTS070RTA,Ready-to-Assay™ ETA Endothelin Receptor Frozen Cells
下一件merck millipore产品:merck millipore,默克密理博,SF-792,FOXO1; Human, Cyanine 3, RNA Detection Probe,SmartFlare



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