merck millipore,默克密理博,AB3572P,Anti-Organic Anion Transporting Polypeptide 2 Antibody, CT, intracellular

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
R	WB, ELISA	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	AB3572P
品牌系列	Chemicon®
商名	Chemicon
描述	Anti-Organic Anion Transporting Polypeptide 2 Antibody, CT, intracellular
Alternate Names	Brain digoxin carrier protein oatp2 OATP-B1
背景信息	Organic Anion Transporting Polypeptide 2 is an integral membrane protein that mediates the sodium-independent transport of organic ions, cardiac glycosides and thyroid hormones. Oatp2 is highly expressed in brain, liver, and kidney but not expressed in heart, spleen, lung, skeletal muscle, or testis.

产品信息
格式	Affinity Purified
演示	Affinity purified immunoglobulin. Liquid in PBS, containing 0.1% BSA.

应用
应用	Detect Organic Anion Transporting Polypeptide 2 using this Anti-Organic Anion Transporting Polypeptide 2 Antibody, C-terminus, intracellular validated for use in ELISA & WB.
主要应用	Western Blotting ELISA
应用说明	Western blot: 1-10 μg/mL using ECL. Rat OATP2 is approximately 75 kD in brain and liver (Noe et al. 1997). ELISA: 0.5-1.0 μg/mL using 1 μg/mL control peptide per well. Optimal working dilutions must be determined by the end user.

生物信息
免疫原品种	A 12 amino acid peptide sequence near the cytoplasmic, C-terminus of rat OATP2. The immunogen shows no significant sequence similarity to other OATPs or other proteins.
表位	C-terminus, intracellular
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
特异性	Recognizes rat Organic Ion Transporter 2 Polypeptide 2.
品种反应性	Rat
抗体类型	Polyclonal Antibody
Entrez基因编号	NM_006446.3
基因符号	OATP-C SLCO1B1 LST1 LST-1 OATP2 OATPC OATP1B1 SLC21A6 MGC133282
UniProt编号	Q9Y6L6
UniProt汇总	FUNCTION: SwissProt: Q9Y6L6 # Mediates the Na(+)-independent transport of organic anions such as pravastatin, taurocholate, methotrexate, dehydroepiandrosterone sulfate, 17-beta-glucuronosyl estradiol, estrone sulfate, prostaglandin E2, thromboxane B2, leukotriene C3, leukotriene E4, thyroxine and triiodothyronine. May play an important role in the clearance of bile acids and organic anions from the liver. SIZE: 691 amino acids; 76449 Da SUBCELLULAR LOCATION: Basolateral cell membrane; Multi-pass membrane protein. Note=Detected in basolateral membranes of hepatocytes. TISSUE SPECIFICITY: Highly expressed in liver. Not detected in heart, brain, placenta, lung, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte. SIMILARITY: SwissProt: Q9Y6L6 ## Belongs to the organo anion transporter (TC 2.A.60) family.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain at -20°C in undiluted aliquots for up to 6 months from date of receipt. Avoid repeated freeze/thaw cycles.

包装信息
数量	50 µg

merck millipore,默克密理博,AB3572P,Anti-Organic Anion Transporting Polypeptide 2 Antibody, CT, intracellular

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