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品种反应性 主要应用 宿主 格式 抗体类型 Rhesus Macaque, H, M, R, Po, B WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB2970 描述 Anti-MAP1LC3B2 Antibody Alternate Names - Microtubule-associated proteins 1A/1B light chain 3B-like
- microtubule-associated protein 1 light chain 3 beta 2
- Microtubule-associated proteins 1A/1B light chain 3B-like protein
- microtubule-associated protein 1 light chain 3 beta-like
- microtubule-associated proteins 1A/1B light chain 3 beta 2
背景信息 Autophagy is the process by which cells recycle cytoplasm and dispose of excess or defective organelles. This process is suggested to be involved in development, differentiation, growth regulation and tissue remodeling in multicellular organisms. The human MAP1LC3 protein is homologous with the rat Map1LC3 and with yeast APG8 proteins. These proteins are likely to be involved in the formation of autophagosomal vacuoles (autophagosomes). 产品信息 格式 Affinity Purified 控制 - HeLa cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect MAP1LC3B2 using this Anti-MAP1LC3B2 Antibody validated for use in WB, IH(P). 主要应用 - Western Blotting
应用说明 Western Blotting (SNAP i.d.® Protein Detection System) Analysis: 5 µg/mL from a previous lot detected MAP1LC3B2 on 10 µg of HeLa cell lysate.
Immunohistochemistry (paraffin) Analysis: A 1:500 dilution from a previous lot detected MAP1LC3B2 in colorectal carcinoma tissue.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human MAP1LC3B2 at the N-terminus. 表位 N-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes MAP1LC3B2 at the N-terminus. 品种反应性 Rhesus MacaqueHumanMouseRatPigBovine Species Reactivity Note Demonstrated to react with human, mouse, and rat.
Predicted to react with bovine, porcine, and rhesus macaque based on 100% sequence homology.
抗体类型 Polyclonal Antibody Entrez基因编号 - A6NCE7
基因符号 - ATG8G
纯化方法 Affinity Purified UniProt编号 - A6NCE7
UniProt汇总 FUNCTION: Probably involved in formation of autophagosomal vacuoles (autophagosomes) By similarity.
SUBUNIT STRUCTURE: 3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins By similarity.
SUBCELLULAR LOCATION: Cytoplasm By similarity. Endomembrane system; Lipid-anchor By similarity. Cytoplasmic vesicle › autophagosome membrane; Lipid-anchor By similarity. Note: LC3-II binds to the autophagic membranes By similarity.
PTM: The precursor molecule is cleaved by APG4B/ATG4B to form LC3-I By similarity. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form LC3-II By similarity.
SEQUENCE SIMILARITIES: Belongs to the MAP1 LC3 family.产品使用声明 质量保证 Evaluated by Western Blot in HeLa cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected MAP1LC3B2 on 10 µg of HeLa cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt 包装信息 数量 100 µg
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