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merck millipore,默克密理博,MABF342,Anti-IL-6 (human) Antibody, FITC, clone MQ2-13A5
产品名称:Anti-IL-6 (human) Antibody, FITC, clone MQ2-13A5
产品型号:MABF342
Detect IL-6 using this rat monoclonal antibody, Anti-IL-6 (human) Antibody, FITC & clone MQ2-13A5 validated for use in Flow Cytometry.
merck millipore,默克密理博,MABF342,Anti-IL-6 (human) Antibody, FITC, clone MQ2-13A5
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H FC R FITC Monoclonal Antibody 描述 产品目录编号 MABF342 描述 Anti-IL-6 (human) Antibody, FITC, clone MQ2-13A5 Alternate Names - IL6
- Interleukin-6
- IL-6
- B-cell stimulatory factor 2
- BSF-2
- CTL differentiation factor
- CDF
- Hybridoma growth factor
- Interferon beta-2
- IFN-beta-2
背景信息 Interleukin-6 (IL-6) is a pro-inflammatory cytokine that seems to be involved in the late stages of CTL generation. Other biological functions also include amplification and the inflammatory response. Combination therapies including IL-6 have been shown to have positive effects on specific malignant tumor types. The accumulation of IL-6 in the CNS is usually detrimental and can contribute to pathology of CNS diseases. IL-6 signaling is negatively regulated by TGF-beta, which down regulates STAT1, STAT3 and ICAM-1 expression. IL-6 expression has been linked to inflammatory bowel disease (IBD) and is also the primary clinical target for IBD. Clinical use of an antibody for the IL-6 receptor (IL-6R) has been promising in treating rheumatoid arthritis, systemic juvenile idiopathic arthritis and Castleman’s disease. 产品信息 格式 FITC 演示 Purified rat conjugate antibody in buffer containing PBS (pH 7.2) with up to 0.1% sodium azide and 0.2% (w/v) BSA. 应用 应用 Detect IL-6 using this rat monoclonal antibody, Anti-IL-6 (human) Antibody, FITC & clone MQ2-13A5 validated for use in Flow Cytometry. 主要应用 - Flow Cytometry
生物信息 免疫原品种 COS-7- expressed, recombinant human IL-6 克隆 MQ2-13A5 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rat 同种型 IgG1κ 品种反应性 Human 抗体类型 Monoclonal Antibody 基因符号 - IFNB2
- IL6
纯化方法 Affinity UniProt编号 - P05231
产品使用声明 质量保证 The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC and unconjugated antibody.
Flow Cytometry Analysis: 5 μL of this antibody detected IL-6 in one million LPS-stimulated human peripheral blood monocytes.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 The antibody solution should be stored undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
包装信息 数量 100 tests
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