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merck millipore,默克密理博,AB1934,Anti-Integrin α1 Subunit Antibody, cytoplasmic/intracellular
产品名称：Anti-Integrin α1 Subunit Antibody, cytoplasmic/intracellular
产品型号：AB1934
This Anti-Integrin α1 Subunit Antibody, cytoplasmic/intracellular is validated for use in ELISA, IP, RIA, WB, IC, IH for the detection of Integrin α1 Subunit.
merck millipore,默克密理博,AB1934,Anti-Integrin α1 Subunit Antibody, cytoplasmic/intracellular
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Sh, Ch, Eq, Gt, H, Ht, Mk, Po, R IHC, ELISA, WB, ICC Rb Serum Polyclonal Antibody 描述 产品目录编号 AB1934 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Integrin α1 Subunit Antibody, cytoplasmic/intracellular Alternate Names - CD49a
产品信息 格式 Serum 演示 Neat rabbit antisera. Liquid containing 0.05% sodium azide as a preservative. 应用 应用 This Anti-Integrin α1 Subunit Antibody, cytoplasmic/intracellular is validated for use in ELISA, IP, RIA, WB, IC, IH for the detection of Integrin α1 Subunit. 主要应用 - Immunohistochemistry
- ELISA
- Western Blotting
- Immunocytochemistry
应用说明 ELISA/RIA: 1:1,000.
Western blot: 1:100-1:1000.
~200 kDa in non-reduced westerns
Immunoprecipitation: 5 μL of antibody is sufficient to precipitate alpha1 containing integrin dimers from 5x10E6 cells (Rossinoi, 1990).
Immunohistochemistry Suggested for use an acetone fixed tissue only. This antibody has been reported to react in 4% PFA fixed monkey tissue treated with citrate at 1:200 (Qin, 2003).
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Synthetic peptide derived from the COOH terminal sequence (cytoplasmic domain) of the rat alpha1 integrin subunit (KIGFFKRPLKKKMEK) coupled to KLH. 表位 cytoplasmic/intracellular 宿主 Rabbit 特异性 Integrin alpha1. Specificity determined by immunoprecipitation from a detergent extract of 35S methionine labeled neuroblastoma cells. The epitope recognized is on the cytoplasmic domain of the protein and it is thus intracellular. No cross-reactivity to alpha2, alpha3, alpha4, alpha5, alpha6, or alphaV integrin subunits. 品种反应性 SheepChickenHorseGoatHumanHamsterMonkeyPigRat 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_181501.1
Entrez基因汇总 This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. 基因符号 - VLA-1
- ITGA1
- CD49a
- VLA1
UniProt编号 - P56199
UniProt汇总 FUNCTION: SwissProt: P56199 # Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G- E-R in collagen.
SIZE: 1179 amino acids; 130848 Da
SUBUNIT: Heterodimer of an alpha and a beta subunit. Alpha-1 associates with beta-1.
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
DOMAIN: SwissProt: P56199 The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
SIMILARITY: Belongs to the integrin alpha chain family. & Contains 7 FG-GAP repeats. & Contains 1 VWFA domain.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to one year from date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µL
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