merck millipore,默克密理愽
  • merck millipore,默克密理博,AB1598P,Anti-Vesicular Monoamine Transporter 2 Antibody

  • merck millipore,默克密理博,AB1598P,Anti-Vesicular Monoamine Transporter 2 Antibody

    产品名称：Anti-Vesicular Monoamine Transporter 2 Antibody
    产品型号：AB1598P
    Anti-Vesicular Monoamine Transporter 2 Antibody is an antibody against Vesicular Monoamine Transporter 2 for use in ELISA, IH & WB.

    merck millipore,默克密理博,AB1598P,Anti-Vesicular Monoamine Transporter 2 Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB1598P,Anti-Vesicular Monoamine Transporter 2 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    RWB, ELISA, IHCRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB1598P
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Vesicular Monoamine Transporter 2 Antibody
    Alternate Names
    • VMAT2
    产品信息
    格式 Affinity Purified
    控制
    • Rat brain tissue
    演示 Liquid in PBS with 0.1% BSA.
    应用
    应用 Anti-Vesicular Monoamine Transporter 2 Antibody is an antibody against Vesicular Monoamine Transporter 2 for use in ELISA, IH & WB.
    主要应用
    • Western Blotting
    • ELISA
    • Immunohistochemistry
    应用说明 Western blot: 1-10 μg/mL (Chemiluminescence technique)

    Immunohistochemistry: 1-20 μg/mL on paraformaldehyde fixed sections.

    ELISA: 0.5-1.0 μg/mL (1 μg/mL VMAT1 peptide (Catalog Number AG251)/well)

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 A 13 amino acid C-terminal peptide sequence from rat VMAT2 (Liu et al. 1992). This peptide is predicted to be cytoplasmic.
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes Vesicular Monoamine Transporter 2 (VMAT2). An antibody made to the C-terminal VMAT2 peptide detected a major band at ~55 kDa in postnuclear supernatants of CHO transfected with VMAT2 and not in wild type cells (Peter et al. 1995; Nirenberg et al. 1995). Some additional bands, both higher and lower molecular weight, were also detected and remain unaffected by the inclusion of protease inhibitors. Higher molecular weight bands may represent glycosylated VMAT2 (Peter et al. 1995; Nirenberg et al. 1995, Liu et al. 1994). VMAT2 has been localized in adrenal chromaffin cells, sympathetic ganglion cells, enterochromaffin-like cells of the stomach and in CNS (Peter et al. 1995; Nirenberg et al. 1995; Nirenberg et al. 1996). May recognize human due to the 92% homology between rat and human VMAT2.
    品种反应性 Rat
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_003054.3
    Entrez基因汇总 The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A1 (MIM 193002).[supplied by OMIM]
    基因符号
    • MGC120478
    • SLC18A2
    • SVAT
    • MGC26538
    • SVMT
    • VAT2
    • MGC120477
    • VMAT2
    纯化方法 Immunoaffinity purified
    UniProt编号
    • Q05940
    UniProt汇总 FUNCTION: SwissProt: Q05940 # Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis.
    SIZE: 514 amino acids; 55713 Da
    SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane; Multi-pass membrane protein.
    SIMILARITY: SwissProt: Q05940 ## Belongs to the major facilitator superfamily. Vesicular transporter family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
    包装信息
    数量 50 µg

    merck millipore,默克密理博,AB1598P,Anti-Vesicular Monoamine Transporter 2 Antibody

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