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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, H ELISA, IHC Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB15065 描述 Anti-Dystonin Antibody Alternate Names - dystonia musculorum of mouse, human homolog of
- 230 kDa bullous pemphigoid antigen
- Bullous pemphigoid antigen
- Dystonia musculorum protein
- Hemidesmosomal plaque protein
- bullous pemphigoid antigen 1, 230/240kDa
背景信息 Dystonin is a cytoskeletal linker protein. It anchors keratin-containing intermediate filaments to the inner plaque of hemidesmosomes. The proteins may self-aggregate to form filaments or a two-dimensional mesh. It is homodimer and interacts with the neuronal intermediate filament protein. 产品信息 格式 Affinity Purified 控制 - Human and mouse brain tissue.
演示 0.1 M Tris-Glycine (pH7.4) 150 mM NaCl with 0.05% sodium azide. 应用 应用 This Anti-Dystonin Antibody is validated for use in IH, ELISA for the detection of Dystonin. 主要应用 - ELISA
- Immunohistochemistry
生物信息 免疫原品种 This antibody is generated from rabbits immunized with a GST-tagged recombinant protein of Dystonin. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes Dystonin. 品种反应性 MouseHuman Species Reactivity Note Demonstrated to react with human and mouse. 抗体类型 Polyclonal Antibody Entrez基因编号 - Q91ZU6
基因符号 - KIAA0728
- KIAA1470
- MACF2
- OTTHUMP00000016657
- OTTHUMP00000040015
- Trabeculin-beta
- dystonin
- BP240
- BPA
- BPAG1
- CATX-15
- D6S1101
- DKFZp564B2416
- DMH
- DT
- Dystonin
- FLJ13425
- FLJ21489
- FLJ30627
- FLJ32235
- FLJ46791
- KIAA0465
纯化方法 Antigen affinity purified UniProt编号 - Q03001
UniProt汇总 FUNCTION: Cytoskeletal linker protein. Anchors keratin-containing intermediate filaments to the inner plaque of hemidesmosomes. The proteins may self-aggregate to form filaments or a two-dimensional mesh.
SUBUNIT STRUCTURE: Homodimer.
SUBCELLULAR LOCATION: Cytoplasm › cytoskeleton.
TISSUE SPECIFICITY: Highly expressed in skeletal muscle and cultured keratinocytes.
INVOLVEMENT IN DISEASE: BPAG1 is an autoantigen of bullous pemphigoid. It is an autoimmune subepithelial skin blistering disease.
SEQUENCE SIMILARITIES: Belongs to the plakin or cytolinker family.
Contains 1 actin-binding domain.
Contains 2 CH (calponin-homology) domains.
Contains 11 plectin repeats.
Contains 1 SH3 domain.
Contains 4 spectrin repeats.产品使用声明 质量保证 Evaluated by ELISA in human and mouse brain tissue.
Immunohistochemistry Analysis: : 1:100 to 1:1,000 dilution of this lot detected Dystonin on human and mouse brain tissue.
使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain refrigerated at 2-8°C for up to 12 months. 包装信息 数量 100 µg
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下一件merck millipore产品：merck millipore,默克密理博,ABE583,Anti-CSTF1 Antibody
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