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  • merck millipore,默克密理博,ABE203,Anti-JARID1D Antibody

  • merck millipore,默克密理博,ABE203,Anti-JARID1D Antibody

    产品名称：Anti-JARID1D Antibody
    产品型号：ABE203
    Use Anti-JARID1D Antibody (rabbit polyclonal antibody) validated in WB, ICC, IP to detect JARID1D also known as Lysine-specific demethylase 5D, Histocompatibility Y antigen, H-Y, Histone demethylase J More>>

    merck millipore,默克密理博,ABE203,Anti-JARID1D Antibody

  • 产品介绍
  • merck millipore,默克密理博,ABE203,Anti-JARID1D Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    M, HICC, WBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 ABE203
    描述 Anti-JARID1D Antibody
    Alternate Names
    • Protein SmcY
    • Lysine-specific demethylase 5D
    • Histocompatibility Y antigen
    • H-Y
    • Histone demethylase JARID1D
    • Jumonji/ARID domain-containing protein 1D
    背景信息 Also known as Lysine-specific demethylase 5D, this histone demethylase is specific for 'Lys-4' of histone H3 and is known to play a central role in histone function and spermatogenesis. It demethylates trimethylated and dimethylated, but not monomethylated H3 'Lys-4'. Uniprot.org states two different isoforms of this enzyme.
    产品信息
    格式 Affinity Purified
    控制
    • Human testis tissue lysate.
    演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Use Anti-JARID1D Antibody (rabbit polyclonal antibody) validated in WB, ICC, IP to detect JARID1D also known as Lysine-specific demethylase 5D, Histocompatibility Y antigen, H-Y, Histone demethylase JARID1D.
    主要应用
    • Immunocytochemistry
    • Western Blotting
    应用说明 Immunocytochemistry Analysis: 2 µg/mL from a representative lot detected JARID1D in mESCs.

    Immunoprecipitation Analysis: A representative lot immunoprecipitated JARID1D in human testis tissue lysate.
    生物信息
    免疫原品种 KLH-conjugated linear peptide corresponding to human JARID1D.
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    品种反应性 MouseHuman
    Species Reactivity Note Demonstrated to react with Human and Mouse.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_004644.2
    Entrez基因汇总 This gene encodes a protein containing zinc finger domains. A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient. Alternative splicing results in multiple transcript variants.
    基因符号
    • SMCY
    • KDM5D
    • HY
    • HYA
    • JARID1D
    • KIAA0234
    纯化方法 Affinity purified
    UniProt编号
    • Q9BY66
    UniProt汇总 FUNCTION: Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis.

    COFACTOR: Ascorbate. Binds 1 Fe2+ ion per subunit.

    SUBUNIT STRUCTURE: Interacts with PCGF6 and MSH5.

    SUBCELLULAR LOCATION: Nucleus.
    产品使用声明
    质量保证 Evaluated by Western Blot in human testis tissue lysate.

    Western Blot Analysis: 0.5 µg/mL of this antibody detected JARID1D in 10 µg of human testis tissue lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,ABE203,Anti-JARID1D Antibody

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