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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Serum Polyclonal Antibody 描述 产品目录编号 AB10088 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-CYP450 1A1 Antibody Alternate Names - Cytochrome P450
产品信息 格式 Serum 演示 Raw Rabbit Serum with 0.1% Sodium Azide 应用 应用 This Anti-CYP450 1A1 Antibody is validated for use in WB for the detection of CYP450 1A1. 主要应用 - Western Blotting
生物信息 免疫原品种 Recombinant CYP450 1A1 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_000499.2
Entrez基因汇总 This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. 基因符号 - AHH
- CYP1A1
- CP11
- P1-450
- CYPIA1
- P450-C
- CYP1
- P450DX
- P450-P1
- AHRR
纯化方法 Serum UniProt编号 - P04798
UniProt汇总 FUNCTION: SwissProt: P04798 # Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
SIZE: 512 amino acids; 58165 Da
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
TISSUE SPECIFICITY: Lung, lymphocytes and placenta.
SIMILARITY: SwissProt: P04798 ## Belongs to the cytochrome P450 family.产品使用声明 质量保证 Routinely evaluated by immunoblot. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 1 year at 2-8°C from date of shipment 包装信息 数量 50 µL
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