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merck millipore,默克密理博,AB10041,Anti-UBXN1/SAKS1 Antibody
产品名称：Anti-UBXN1/SAKS1 Antibody
产品型号：AB10041
Use Anti-UBXN1/SAKS1 Antibody (Rabbit Polyclonal Antibody) validated in WB, IP to detect UBXN1/SAKS1 also known as SAPK substrate protein 1, UBA/UBX 33.3 kDa protein.
merck millipore,默克密理博,AB10041,Anti-UBXN1/SAKS1 Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, H, R WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB10041 描述 Anti-UBXN1/SAKS1 Antibody Alternate Names - UBX domain protein 1
- SAPK substrate protein 1
- UBA/UBX 33.3 kDa protein
背景信息 UBX domain-containing protein 1 (UBXN1 or SAKS1) is a component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol. UBX domain-containing protein 1 is also involved in ubiquitin-proteasome systems. 产品信息 格式 Affinity Purified 控制 - Human fetal brain tissue lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Use Anti-UBXN1/SAKS1 Antibody (Rabbit Polyclonal Antibody) validated in WB, IP to detect UBXN1/SAKS1 also known as SAPK substrate protein 1, UBA/UBX 33.3 kDa protein. 主要应用 - Western Blotting
应用说明 Immunoprecipitation Analysis: 20 µg from a previous lot of this antibody was used in immunoprecipitation in 1 mL of mouse brain tissue lysate.
Western Blot (SNAP ID) Analysis: 2 µg/mL from a previous lot detected UBX domain-containing protein 1 in 10 µg of human fetal tissue lysate.生物信息 免疫原品种 GST-tagged recombinant protein corresponding to full-length human UBX domain-containing protein 1. 表位 Full Length Protein 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes full-length UBX domain-containing protein 1. 品种反应性 MouseHumanRat Species Reactivity Note Demonstrated to react with human. mouse and rat. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_056937.2
基因符号 - UBXD10
- 2B28
- LOC51035
- SAKS1
纯化方法 Affinity Purfied UniProt编号 - Q04323
UniProt汇总 FUNCTION: Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulun that are retrotranslocated in the cytosol. Involved in ubiquitin-proteasome systems By similarity.
SUBUNIT STRUCTURE: Component of a complex required to couple retrotranslocation, ubiquitination and deglycosylation composed of NGLY1, SAKS1, AMFR, VCP and RAD23B. Interacts with HOMER2 By similarity. Interacts directly with VCP. Binds polyubiquitin.
SUBCELLULAR LOCATION: Cytoplasm By similarity.
SEQUENCE SIMILARITIES: Contains 1 UBA domain.
Contains 1 UBX domain.产品使用声明 质量保证 Evaluated by Western Blot in human fetal brain lysate.
Western Blot Analysis: 0.1 µg/mL of this antibody detected UBX domain-containing protein 1 in 10 µg of human fetal brain lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable at 2-8°C for 1 year from date of recepit. 包装信息 数量 100 µg
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