merck millipore,默克密理愽
  • merck millipore,默克密理博,681667,Wnt Agonist II, SKL2001 - Calbiochem

  • merck millipore,默克密理博,681667,Wnt Agonist II, SKL2001 - Calbiochem

    产品名称：Wnt Agonist II, SKL2001 - Calbiochem
    产品型号：681667
    The Wnt Agonist II, SKL2001 controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Biochemicals applications.

    merck millipore,默克密理博,681667,Wnt Agonist II, SKL2001 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,681667,Wnt Agonist II, SKL2001 - Calbiochem

    重要规格表

    经验配方
    C₁₄H₁₄N₄O₃
    描述
    概述 A cell-permeable imidazolyl-isoxazolamide that upregulates β-catenin-regulated transcription (CRT; 10 - 40 µM) by disrupting β-catenin and Axin interaction, thereby preventing β-catenin phosphorylation (Ser33/Ser37/Thr41/Ser45) and proteasomal degradation, without affecting the activities of GSK-3α/β or 18 other kinases (≤8.5% inhibition by 10 µM SKL2001). Shown to effectively promote osteoblastogenesis in both human and murine mesenchymal cultures (10 to 40 µM) as well as suppress MDI- (dexamethasone and insulin) stimulated adipogenesis of murine 3T3-L1 preadipocytes (5 to 30 µM).
    产品目录编号 681667
    品牌系列 Calbiochem®
    同义词 5-(Furan-2-yl)-N-(3-(1H-imidazol-1-yl)propyl)-1,2-oxazole-3-carboxamide, Wnt Pathway Activator VII
    参考
    参考 Gwak, J., et al. 2012. Cell Res. 22, 237.
    产品信息
    形式 Pinkish red solid
    Hill配方 C₁₄H₁₄N₄O₃
    化学配方 C₁₄H₁₄N₄O₃
    Molar Mass 286.3
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,681667,Wnt Agonist II, SKL2001 - Calbiochem

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下一件merck millipore产品：merck millipore,默克密理博,ABT341,Anti-KLHL1 Antibody


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