merck millipore,默克密理愽
  • merck millipore,默克密理博,681635,W-12, Hydrochloride - CAS 89108-46-3 - Calbiochem

  • merck millipore,默克密理博,681635,W-12, Hydrochloride - CAS 89108-46-3 - Calbiochem

    产品名称：W-12, Hydrochloride - CAS 89108-46-3 - Calbiochem
    产品型号：681635
    A cell-permeable and reversible calmodulin antagonist that inhibits myosin light chain kinase (IC₅₀ = 300 µM) and Ca2+-calmodulin-dependent phosphodiesterase (IC₅₀ = 260 µM).

    merck millipore,默克密理博,681635,W-12, Hydrochloride - CAS 89108-46-3 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,681635,W-12, Hydrochloride - CAS 89108-46-3 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₄H₁₈N₂O₂S · HCl89108-46-3
    描述
    概述 A cell-permeable and reversible calmodulin antagonist that inhibits myosin light chain kinase (IC50 = 300 µM) and Ca2+-calmodulin-dependent phosphodiesterase (IC50 = 260 µM).
    产品目录编号 681635
    品牌系列 Calbiochem®
    同义词 N-(4-Aminobutyl)-2-naphthalenesulfonamide, HCl
    参考
    参考 Tanaka, T., et al. 1983. Pharmacol. 26, 249.
    Asano, M., et al. 1982. J. Pharmacol. Exp. Ther. 220, 191.
    Hidaka, H. 1981. Prot. Nuc. Acid Enz. 26, 977.
    Tanaka, T., and Hidaka, H. 1980. J. Biol. Chem. 255, 11078.
    产品信息
    CAS号 89108-46-3
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₁₄H₁₈N₂O₂S · HCl
    化学配方 C₁₄H₁₈N₂O₂S · HCl
    Molar Mass 314.8
    吸湿 Hygroscopic
    可逆 Y
    结构配方图像
    生物信息
    主靶 Myosin light chain kinase (Mlck)
    主靶IC50 300 µM and 260 µM against myosin light chain kinase and Ca2+-calmodulin-dependent phosphodiesterase, respectively.
    纯度 ≥97% by TLC
    理化信息
    细胞可渗透 Y
    溶解度 EtOH or H₂O
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

    merck millipore,默克密理博,681635,W-12, Hydrochloride - CAS 89108-46-3 - Calbiochem

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