• merck millipore,默克密理博,681525,Wiskostatin - CAS 253449-04-6 - Calbiochem
  • merck millipore,默克密理博,681525,Wiskostatin - CAS 253449-04-6 - Calbiochem

    产品名称:Wiskostatin - CAS 253449-04-6 - Calbiochem
    产品型号:681525
    A cell-permeable N-alkylated carbazole derivative that selectively blocks actin filament assembly.

    merck millipore,默克密理博,681525,Wiskostatin - CAS 253449-04-6 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,681525,Wiskostatin - CAS 253449-04-6 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₇H₁₈Br₂N₂O253449-04-6
    描述
    概述 A cell-permeable N-alkylated carbazole derivative that selectively blocks actin filament assembly. Acts as a selective, reversible inhibitor of N-WASP (neural Wiskott Aldrich syndrome protein), a signal integrating protein. Appears to bind to N-WASP, stabilize the autoinhibited conformation and prevent the activation of Arp2/3 (actin-related protein 2/3) complex.
    产品目录编号 681525
    品牌系列 Calbiochem®
    参考
    参考 Peterson, J.R., et al. 2004. Nat. Struct. Mol. Biol. 11, 747.
    Peterson, J.R., and Mitchison, T.J. 2002. Chem. Biol. 9, 1275.
    产品信息
    CAS号 253449-04-6
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₁₇H₁₈Br₂N₂O
    化学配方 C₁₇H₁₈Br₂N₂O
    Molar Mass 426.2
    可逆 Y
    结构配方图像
    生物信息
    主靶 N-WASP (neural Wiskott Aldrich syndrome protein)
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,681525,Wiskostatin - CAS 253449-04-6 - Calbiochem

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