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经验配方 CAS号 C₁₆H₁₅N₃O₃ 211555-08-7 描述 概述 A potent inhibitor of lgE-mediated mast cell responses to allergens in vitro and in vivo. Also inhibits cyclin-dependent kinase 2 (Cdk2; IC50 = 1 µM) by blocking the ATP site. 产品目录编号 681500 品牌系列 Calbiochem®
同义词 4-(3ʹ-Hydroxyphenyl)amino-6,7-dimethoxyquinazoline 参考 参考 Shewchuk, L., et al. 2000. J. Med. Chem. 43, 133.
Chen, C.L., et al. 1999. Pharm. Res. 16, 117.产品信息 CAS号 211555-08-7 具有ATP竞争性 N 形式 Pale yellow solid Hill配方 C₁₆H₁₅N₃O₃ 化学配方 C₁₆H₁₅N₃O₃ Molar Mass 297.3 可逆 N 结构配方图像 生物信息 主靶 Cdk2 主靶IC50 1 µM for Cdk2 纯度 ≥98% by HPLC 理化信息 细胞可渗透 N 溶解度 DMSO 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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