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主要应用 HDAC 描述 产品目录编号 20-221 品牌系列 Upstate
商名 - Upstate
描述 NAD Cofactor 概述 Description: β-nicotinamide adenine dinucleotide hydrate
FW: 663.4
Use: Can be used as a cofactor in reactions with NAD-dependent histone deacetylase enzymes.产品信息 演示 lyophilized powder 应用 应用 Can be used as a cofactor in reactions with NAD-dependent histone deacetylase enzymes. 主要应用 - Histone Deacetylase Assay (HDAC)
生物信息 Entrez基因编号 - NM_005530.2
Entrez基因汇总 Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. 基因符号 - NAD
- IDH3A
UniProt编号 - P50213
UniProt汇总 COFACTOR: Binds 1 magnesium or manganese ion per subunit (By similarity).
SIZE: 366 amino acids; 39592 Da
SUBUNIT: Heterooligomer of subunits alpha, beta, and gamma in the apparent ratio of 2:1:1 (By similarity).
SUBCELLULAR LOCATION: Mitochondrion.
SIMILARITY: SwissProt: P50213 ## Belongs to the isocitrate and isopropylmalate dehydrogenases family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 1 year at room temperature 包装信息 数量 10 mg
上一件merck millipore产品：merck millipore,默克密理博,47-233,MILLIPLEX MAP HEH293 Cell Lysate: Serum - Lysates/Reagents for Multiplex Assays
下一件merck millipore产品：merck millipore,默克密理博,681500,WHI-P180
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