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经验配方 CAS号 C₁₁H₈N₂O 2826-26-8 描述 概述 An inactive compound that can be used as a negative control for inhibition of EGFR (IC50 >1250 µM for EGFR kinase). Has been shown to inhibit IL-2 stimulated Tyk-2 phosphorylation in ConA-activated T cells. 产品目录编号 658390 品牌系列 Calbiochem®
同义词 [(4-Methoxybenzylidene)malononitrile, α-Cyano-(4-methoxy)cinnamonitrile], Tyrphostin A1 参考 参考 Bright, J.J., et al. 1999. J. Immunol. 162, 6255.
Gazit, A., et al. 1989. J. Med. Chem. 32, 2344.
Ruetten, H. and Thiemermann, C. 1997. Br. J. Pharmacol. 122, 59.产品信息 CAS号 2826-26-8 具有ATP竞争性 N 形式 Yellow solid Hill配方 C₁₁H₈N₂O 化学配方 C₁₁H₈N₂O Molar Mass 184.2 可逆 N 结构配方图像 生物信息 主靶 negative control for inhibition of EGFR 主靶IC50 >1250 µM for EGFR kinase 纯度 ≥98% by TLC 理化信息 细胞可渗透 N 溶解度 Acetic acid, DMSO, or EtOH 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
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