merck millipore,默克密理愽
  • merck millipore,默克密理博,648450,TrkA Inhibitor - CAS 388626-12-8 - Calbiochem

  • merck millipore,默克密理博,648450,TrkA Inhibitor - CAS 388626-12-8 - Calbiochem

    产品名称：TrkA Inhibitor - CAS 388626-12-8 - Calbiochem
    产品型号：648450
    The TrkA Inhibitor, also referenced under CAS 388626-12-8, controls the biological activity of TrkA. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation application More>>

    merck millipore,默克密理博,648450,TrkA Inhibitor - CAS 388626-12-8 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,648450,TrkA Inhibitor - CAS 388626-12-8 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₅H₁₃N₃O₃S388626-12-8
    描述
    概述 An oxindole compound that acts as a cell-permeable, reversible, potent, and highly selective inhibitor of TrkA (IC50 = 63 nM), presumably by targeting the kinase’s ATP binding pocket. Shown to exhibit ≥150-fold selectivity over Cdk1 and cRaf1.
    产品目录编号 648450
    品牌系列 Calbiochem®
    参考
    参考 Wood, E.R., et al. 2004. Bioorg. Med. Chem. Lett. 14, 953.
    产品信息
    CAS号 388626-12-8
    具有ATP竞争性 N
    形式 Yellow solid
    Hill配方 C₁₅H₁₃N₃O₃S
    化学配方 C₁₅H₁₃N₃O₃S
    Molar Mass 315.4
    可逆 Y
    结构配方图像
    生物信息
    主靶 TrkA
    主靶IC50 63 nM against TrkA
    纯度 ≥97% by HPLC (sum of two isomers)
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,648450,TrkA Inhibitor - CAS 388626-12-8 - Calbiochem

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