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经验配方 CAS号 C₂₆H₂₉NO · C₆H₈O₇ 54965-24-1 描述 概述 A potent synthetic anti-estrogenic agent. A cell-permeable and reversible inhibitor of protein kinase C (IC50 = 10 µM). Induces apoptosis in human malignant glioma cell lines and inhibits prostate cancer cell growth by induction of p21 protein. 产品目录编号 579000 品牌系列 Calbiochem®
同义词 Estrogen Receptor Signaling Regulator I 参考 参考 Rohlff, C., et al. 1998. Prostate 37, 51.
Couldwell, W.J., et al. 1994. FEBS Lett. 345, 43.
Baltuch, G.H., et al. 1993. Neurosurgery 33, 495.
Powis, G. 1991. Trends Pharmacol. Sci. 12, 188.
Issandou, M., et al. 1990. Cancer Res. 50, 5845.
O’Brian, C.A., et al. 1985. Cancer Res. 45, 2462.产品信息 CAS号 54965-24-1 具有ATP竞争性 N 形式 White to off-white powder Hill配方 C₂₆H₂₉NO · C₆H₈O₇ 化学配方 C₂₆H₂₉NO · C₆H₈O₇ Molar Mass 563.7 可逆 Y 结构配方图像 生物信息 主靶 PKC 主靶IC50 10 µM against protein kinase C 纯度 ≥99% by HPLC 理化信息 细胞可渗透 Y 溶解度 EtOH or MeOH GHS安全信息 RTECS KH2387000 安全信息 R相 R: 22-45-60-61-64
Harmful if swallowed.
May cause cancer.
May impair fertility.
May cause harm to the unborn child.
May cause harm to breastfed babies.S相 S: 36/37/39-45
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).储存和货运信息 货运代码 Ambient Temperature Only
毒性 Harmful & Carcinogenic / Teratogenic
储存 +2°C to +8°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
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