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经验配方 CAS号 C₁₉H₂₁N₃O₃S 330161-87-0 描述 概述 A potent, cell-permeable, reversible, and ATP-competitive Src family kinase inhibitor. Inhibits Src (IC50 = 280 nM) as well as closely related kinases such as Fyn (IC50 = 170 nM) and Yes (IC50 = 20 nM) and Lyn (IC50 = 130 nM). Acts as a weak inhibitor of Lck (IC50 = 688 µM) and PDGF receptor kinase (IC50 >10 µM). A 10 mM (500 µg/135 µl) solution of SU6656 (Cat. No. 572636) in DMSO is also available. 产品目录编号 572635 品牌系列 Calbiochem®
参考 参考 Bowman, T., et al. 2001. Proc. Natl. Acad. Sci. USA 98, 7319.
Blake, R.A., et al. 2000. Mol. Cell. Biol. 20, 9018.产品信息 CAS号 330161-87-0 具有ATP竞争性 Y 形式 Burnt orange solid Hill配方 C₁₉H₂₁N₃O₃S 化学配方 C₁₉H₂₁N₃O₃S Molar Mass 371.5 可逆 Y 结构配方图像 生物信息 主靶 Src 主靶IC50 280 nM, 170 nM, 20 nM, and 130 nM against Src, Fyn, Yes, and Lyn. 纯度 ≥97% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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