merck millipore,默克密理愽
  • merck millipore,默克密理博,567300,SKF-525A, Hydrochloride - CAS 62-68-0 - Calbiochem

  • merck millipore,默克密理博,567300,SKF-525A, Hydrochloride - CAS 62-68-0 - Calbiochem

    产品名称：SKF-525A, Hydrochloride - CAS 62-68-0 - Calbiochem
    产品型号：567300
    Cell permeable. Blocks glibenclamide-sensitive K+ channels. Inhibits neuronal nitric oxide synthase. Also inhibits hepatic drug metabolism by inhibiting the cytochrome P450 system.

    merck millipore,默克密理博,567300,SKF-525A, Hydrochloride - CAS 62-68-0 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,567300,SKF-525A, Hydrochloride - CAS 62-68-0 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₃H₃₁NO₂ . HCl62-68-0
    描述
    概述 Cell permeable. Blocks glibenclamide-sensitive K+ channels. Inhibits neuronal nitric oxide synthase (IC50 = 90 µM). Also inhibits hepatic drug metabolism by inhibiting the cytochrome P450 system. Stimulates endothelial cell prostacyclin production while inhibiting platelet thromboxane synthesis. Potentiates the action of many drugs in vivo.
    产品目录编号 567300
    品牌系列 Calbiochem®
    同义词 Proadifen
    参考
    参考 Hecker, M., et al. 1994. J. Neurochem. 62, 1524.
    Sakuta, H. and Yoneda, I. 1994. Eur. J. Pharmacol. 252, 117.
    Khan, S., et al. 1993. Biochem. Pharmacol. 45, 439.
    Boeynaems, J.M., et al. 1986. Prostaglandins 32, 145.
    Lee, C.H., et al. 1976. J. Pharmacol. Exp. Ther. 198, 347.
    Grasdalen, J., et al. 1975. FEBS Lett. 60, 240.
    产品信息
    CAS号 62-68-0
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₂₃H₃₁NO₂ . HCl
    化学配方 C₂₃H₃₁NO₂ . HCl
    Molar Mass 390.0
    吸湿 Hygroscopic
    可逆 N
    结构配方图像
    生物信息
    主靶 nNOS
    主靶IC50 90 µM against neuronal nitric oxide synthase
    纯度 ≥98% by TLC
    理化信息
    细胞可渗透 Y
    溶解度 H₂O
    GHS安全信息
    RTECS YV7175000
    安全信息
    R相 R: 22

    Harmful if swallowed.
    S相 S: 36

    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Harmful
    储存 -20°C
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, store in the refrigerator(4°C). Stock solutions are stable for up to 6 months at 4°C.

    merck millipore,默克密理博,567300,SKF-525A, Hydrochloride - CAS 62-68-0 - Calbiochem

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