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merck millipore,默克密理博,566330,SIRT1/2 Inhibitor VIII, Salermide - CAS 1105698-15-4 - Calbiochem
产品名称：SIRT1/2 Inhibitor VIII, Salermide - CAS 1105698-15-4 - Calbiochem
产品型号：566330
The SIRT1/2 Inhibitor VIII, Salermide, also referenced under CAS 1105698-15-4, controls the biological activity of SIRT1/2. This small molecule/inhibitor is primarily used for Cell Structure applicati More>>
merck millipore,默克密理博,566330,SIRT1/2 Inhibitor VIII, Salermide - CAS 1105698-15-4 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₂₆H₂₂N₂O₂ 1105698-15-4 描述 概述 A cell-permeable 2-hydroxy-naphthaldehyde that acts as an inhibitor against sirtuins SirT1 and SirT2, members of class III HDACs. Salermide effectively inhibits the activity of both SirT1 and SirT2 (by 80% at 100 and 25 µM, respectively), while its structural analogue Sirtinol (Cat. Nos. 566320 and 566321), at 100 µM concentration, inhibits SirT2 only by up to 60% and is of no effect against SirT1. Salermide is also shown to be at least 2-fold more potent than Sirtinol (both at 100 µM) in killing leukemia KG1A and lymphoma Raji cultures. 产品目录编号 566330 品牌系列 Calbiochem®
同义词 N-(3-((2-Hydroxynaphthalen-1-ylmethylene)-amino)-phenyl)-2-phenyl-propionamide, SIRT1 Inhibitor VI, SIRT2 Inhibitor VIII 参考 参考 Lara, E., et al. 2009. Oncogene 28, 781. 产品信息 CAS号 1105698-15-4 形式 Yellow solid Hill配方 C₂₆H₂₂N₂O₂ 化学配方 C₂₆H₂₂N₂O₂ Molar Mass 394.5 结构配方图像 生物信息 纯度 ≥95% by HPLC 理化信息 溶解度 DMSO 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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