merck millipore,默克密理愽
  • merck millipore,默克密理博,565835,SHIP1 Inhibitor, 3AC - Calbiochem

  • merck millipore,默克密理博,565835,SHIP1 Inhibitor, 3AC - Calbiochem

    产品名称：SHIP1 Inhibitor, 3AC - Calbiochem
    产品型号：565835
    The SHIP1 Inhibitor, 3AC controls the biological activity of SHIP1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

    merck millipore,默克密理博,565835,SHIP1 Inhibitor, 3AC - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,565835,SHIP1 Inhibitor, 3AC - Calbiochem

    重要规格表

    经验配方
    C₂₇H₄₉N
    描述
    概述 A cell-permeable steroidal compound that selectively inhibits SHIP1′ polyphosphatase activity toward PI(3,4,5)P3 (IC50 = 10 µM), but not SHIP2 5′ or PTEN′ polyphosphatase activity toward PI(3,4,5)P3 (IC50 > 1 mM). Effectively inhibits SHIP1-mediated immune response both in vitro and in vivo, as well as SHIP1-dependent cancer cell survival. SHIP2 Inhibitor, AS1938909 is also available (Cat. No. 565840).
    产品目录编号 565835
    品牌系列 Calbiochem®
    同义词 3α-Aminocholestane, SH2-domain-containing inositol 5ʹ-phosphatase 1 (SHIP1) Inhibitor, 3AC
    参考
    参考 Brooks, R., et al. 2010. J. Immunol. 184, 3582.
    产品信息
    形式 White solid
    Hill配方 C₂₇H₄₉N
    化学配方 C₂₇H₄₉N
    Molar Mass 387.7
    结构配方图像
    生物信息
    纯度 ≥98% by 1H NMR
    理化信息
    溶解度 EtOH
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 +2°C to +8°C
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,565835,SHIP1 Inhibitor, 3AC - Calbiochem

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