• merck millipore,默克密理博,557354,ROS Inhibitor, YCG063 - CAS 330997-95-0 - Calbiochem
  • merck millipore,默克密理博,557354,ROS Inhibitor, YCG063 - CAS 330997-95-0 - Calbiochem

    产品名称:ROS Inhibitor, YCG063 - CAS 330997-95-0 - Calbiochem
    产品型号:557354
    The ROS Inhibitor, YCG063, also referenced under CAS 330997-95-0, controls the biological activity of ROS.

    merck millipore,默克密理博,557354,ROS Inhibitor, YCG063 - CAS 330997-95-0 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,557354,ROS Inhibitor, YCG063 - CAS 330997-95-0 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₉H₂₅N₅O₄S330997-95-0
    描述
    概述 A cell-permeable acetohydrazide that dose-dependently inhibits hypoxia-induced mitochondrial ROS generation (≤ 10 µM) in HepG2 and other cells, and suppresses cellular growth (≤ 50 µM) in HUVEC, HeLa, and HCT15 cultures. At ≤ 10 µM, this compound strongly inhibits VGFR-induced tube formation and invasive activity in HUVECs in vitro without obvious toxicity. It is also shown to hinder capillary formation in a chick embryo CAM assay without any sign of thrombosis and hemorrhage in vivo. Furthermore, it attenuates the expression levels HIF-1α and its target gene VEGF (0–10 µM). dose-dependently.
    产品目录编号 557354
    品牌系列 Calbiochem®
    同义词 YCG063 ROS Inhibitor
    参考
    参考 Kim, K.H., et al. 2011. Biochem. Biophys. Res. Commun. 404, 541.
    产品信息
    CAS号 330997-95-0
    形式 White solid
    Hill配方 C₁₉H₂₅N₅O₄S
    化学配方 C₁₉H₂₅N₅O₄S
    Molar Mass 419.5
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO or EtOH
    储存和货运信息
    货运代码 Shipped with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,557354,ROS Inhibitor, YCG063 - CAS 330997-95-0 - Calbiochem

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