merck millipore,默克密理愽
  • merck millipore,默克密理博,555556,Rho Kinase Inhibitor VII - Calbiochem

  • merck millipore,默克密理博,555556,Rho Kinase Inhibitor VII - Calbiochem

    产品名称：Rho Kinase Inhibitor VII - Calbiochem
    产品型号：555556
    The Rho Kinase Inhibitor VII controls the biological activity of Rho Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

    merck millipore,默克密理博,555556,Rho Kinase Inhibitor VII - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,555556,Rho Kinase Inhibitor VII - Calbiochem

    重要规格表

    经验配方
    C₂₁H₂₄N₈
    描述
    概述 A cell-permeable triaminotriazine ROCK inhibitor (IC50 = 6 nM in a cell-free ROCK1 kinase assay) that affects 24 other commonly studied non-ROCK kinases only at much higher concentrations (IC50 > 2 µM) and effectively blocks MCP-1-induced THP-1 cell migration (IC50 = 30 nM) in vitro. Subcutaneous injection (3-10 mg/kg) of ROCK Inhibitor VII and oral dosing (30 mg/kg) of Y-27632 (Cat. Nos. 688000 & 688001) are both reported to significantly reduce arterial blood pressure in a spontaneous hypertensive rat model in vivo.
    产品目录编号 555556
    品牌系列 Calbiochem®
    同义词 ROCK Inhibitor VII, Rho Kinase Inhibitor VII
    参考
    参考 Ho, K.K., et al. 2009. Bioorg. Med. Chem. Lett. 19, 6027.
    产品信息
    形式 Light beige solid
    Hill配方 C₂₁H₂₄N₈
    化学配方 C₂₁H₂₄N₈
    Molar Mass 388.5
    吸湿 Hygroscopic
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO or H₂O
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,555556,Rho Kinase Inhibitor VII - Calbiochem

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