merck millipore,默克密理愽
  • merck millipore,默克密理博,540210,PTP Inhibitor III - CAS 29936-81-0 - Calbiochem

  • merck millipore,默克密理博,540210,PTP Inhibitor III - CAS 29936-81-0 - Calbiochem

    产品名称：PTP Inhibitor III - CAS 29936-81-0 - Calbiochem
    产品型号：540210
    The PTP Inhibitor III, also referenced under CAS 29936-81-0, controls the biological activity of PTP. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applicatio More>>

    merck millipore,默克密理博,540210,PTP Inhibitor III - CAS 29936-81-0 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,540210,PTP Inhibitor III - CAS 29936-81-0 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₀H₉BrO₄29936-81-0
    描述
    概述 A potent, cell-permeable, and covalent protein tyrosine phosphatase (PTP) inhibitor. Binds to SHP-1 (ΔSH2), the catalytic domain of the SH2 domain-containing phosphatase SHP-1, with lower affinity than PTP Inhibitor I (Cat. No. 540200) (Ki = 193 µM versus Ki = 43 µM) but with a higher kinact (1.8 min-1 versus 0.4 min-1). The inhibition can be reversed by irradiation of the inactivated PTP at 350 nm.
    产品目录编号 540210
    品牌系列 Calbiochem®
    同义词 α-Bromo-4-(carboxymethoxy)acetophenone, 4-(Carboxymethoxy)phenacyl Br, Protein Tyrosine Phosphatase Inhibitor III, SHP1 Inhibitor III, PTP-MEG2/PTPN9 Inhibitor, PTP-β Inhibitor, PTP-δ Inhibitor, PTP-ε Inhibitor, PTP-µ Inhibitor, PTP1B Inhibitor III, SHP2 Inhibitor II
    参考
    参考 Arabaci, G., et al. 1999. J. Am. Chem. Soc. 121, 5085.
    产品信息
    CAS号 29936-81-0
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₁₀H₉BrO₄
    化学配方 C₁₀H₉BrO₄
    Molar Mass 273.1
    可逆 Y
    结构配方图像
    生物信息
    主靶 protein tyrosine phosphatase (PTP)
    主靶IC50 193 µM against PTP
    纯度 ≥90% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    安全信息
    R相 R: 34-36/37

    Causes burns.
    Irritating to eyes and respiratory system.
    S相 S: 26-27-28-36/37/39

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Take off immediately all contaminated clothing.

    Wear suitable protective clothing, gloves and eye/face protection.
    储存和货运信息
    货运代码 Blue Ice Only
    毒性 Corrosive
    有害材料注意事项： Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
    储存 ≤ -70°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Unstable in DMSO; reconstitute just prior to use. Following initial thaw, aliquot and freeze (-70°C).
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,540210,PTP Inhibitor III - CAS 29936-81-0 - Calbiochem

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