• merck millipore,默克密理博,540200,PTP Inhibitor I - CAS 2491-38-5 - Calbiochem
  • merck millipore,默克密理博,540200,PTP Inhibitor I - CAS 2491-38-5 - Calbiochem

    产品名称:PTP Inhibitor I - CAS 2491-38-5 - Calbiochem
    产品型号:540200
    The PTP Inhibitor I, also referenced under CAS 2491-38-5, controls the biological activity of PTP. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

    merck millipore,默克密理博,540200,PTP Inhibitor I - CAS 2491-38-5 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,540200,PTP Inhibitor I - CAS 2491-38-5 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₈H₇BrO₂2491-38-5
    描述
    概述 A potent, cell-permeable, and covalent protein tyrosine phosphatase (PTP) inhibitor. Inhibits SHP-1 (ΔSH2), the catalytic domain of the SH2 domain-containing phosphatase SHP-1 (Ki = 43 µM), and PTPIB (Ki = 42 µM). The inhibition can be reversed by irradiation of the inactivated PTP at 350 nm.
    产品目录编号 540200
    品牌系列 Calbiochem®
    同义词 Protein Tyrosine Phosphatase Inhibitor I, α-Bromo-4-hydroxyacetophenone, 4-Hydroxyphenacyl Br, SHP1 Inhibitor II
    参考
    参考 Arabaci, G., et al. 1999. J. Am. Chem. Soc. 121, 5085.
    产品信息
    CAS号 2491-38-5
    具有ATP竞争性 N
    形式 White powder
    Hill配方 C₈H₇BrO₂
    化学配方 C₈H₇BrO₂
    Molar Mass 215.1
    可逆 N
    结构配方图像
    生物信息
    主靶 SHP-1
    主靶IC50 43 µM
    主靶Ki 43 µM and 42 µM against SHP-1 and PTPIB, respectively
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    安全信息
    R相 R: 34-36/37

    Causes burns.
    Irritating to eyes and respiratory system.
    S相 S: 26-27-28-36/37/39

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Take off immediately all contaminated clothing.

    Wear suitable protective clothing, gloves and eye/face protection.
    储存和货运信息
    货运代码 Blue Ice Only
    毒性 Corrosive
    有害材料注意事项: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
    储存 ≤ -70°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Unstable in DMSO; reconstitute just prior to use.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,540200,PTP Inhibitor I - CAS 2491-38-5 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,MABE171,Anti-phospho-Histone H2A.X (Thr120) Antibody, clone 11F5.3
下一件merck millipore产品:merck millipore,默克密理博,251650,Damnacanthal - CAS 477-84-9 - Calbiochem



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