merck millipore,默克密理愽
  • merck millipore,默克密理博,539749,InSolution™ PTP1B Inhibitor - Calbiochem

  • merck millipore,默克密理博,539749,InSolution™ PTP1B Inhibitor - Calbiochem

    产品名称：InSolution™ PTP1B Inhibitor - Calbiochem
    产品型号：539749
    The InSolution™ PTP1B Inhibitor controls the biological activity of PTP1B. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

    merck millipore,默克密理博,539749,InSolution™ PTP1B Inhibitor - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,539749,InSolution™ PTP1B Inhibitor - Calbiochem

    重要规格表

    经验配方
    C₂₆H₁₉Br₂N₃O₇S₃
    描述
    概述 A cell-permeable, selective, reversible, and non-competitive allosteric inhibitor of PTP1B (IC50 = 4 µM and 8 µM for PTP1B403 and PTP1B298, respectively). Binds to a novel site away from the catalytic pocket and inhibits PTP1B activity by preventing closure of the WPD loop.
    产品目录编号 539749
    品牌系列 Calbiochem®
    同义词 PTP Inhibitor XXII
    参考
    参考 Wiesmann, C., et al. 2004. Nat. Struct. Mol. Biol. 11, 730.
    产品信息
    形式 Liquid
    配方 A 10 mM (2 mg/270 µl) solution of PTP1B Inhibitor (Cat. No. 539741) in DMSO.
    Hill配方 C₂₆H₁₉Br₂N₃O₇S₃
    化学配方 C₂₆H₁₉Br₂N₃O₇S₃
    Molar Mass 741.5
    吸湿 Hygroscopic
    可逆 Y
    结构配方图像
    生物信息
    主靶IC50 IC50 = 4 and 8 µM for PTP1B403 and PTP1B298, respectively
    纯度 ≥97% by HPLC
    理化信息
    细胞可渗透 Y
    安全信息
    R相 R: 36/38

    Irritating to eyes and skin.
    储存和货运信息
    货运代码 Dry Ice Only
    毒性 Irritant
    储存 -20°C
    避光 Protect from light
    吸湿 Hygroscopic
    避免冻结 / 解冻 Avoid freeze/thaw
    无需冷冻 No
    特殊指南 Following initial thaw, aliquot and freeze (-20°C).
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,539749,InSolution™ PTP1B Inhibitor - Calbiochem

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