merck millipore,默克密理愽
  • merck millipore,默克密理博,539209,Protein Arginine N-Methyltransferase Inhibitor, AMI-1 - Calbiochem

  • merck millipore,默克密理博,539209,Protein Arginine N-Methyltransferase Inhibitor, AMI-1 - Calbiochem

    产品名称：Protein Arginine N-Methyltransferase Inhibitor, AMI-1 - Calbiochem
    产品型号：539209
    The Protein Arginine N-Methyltransferase Inhibitor, AMI-1 controls the biological activity of Protein Arginine N-Methyltransferase. This small molecule/inhibitor is primarily used for Protease Inhibit More>>

    merck millipore,默克密理博,539209,Protein Arginine N-Methyltransferase Inhibitor, AMI-1 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,539209,Protein Arginine N-Methyltransferase Inhibitor, AMI-1 - Calbiochem

    重要规格表

    经验配方
    C₂₁H₁₂N₂Na₄O₉S₂
    描述
    概述 A cell-permeable, symmetrical sulfonated urea compound that acts as a potent, specific and non-AdoMet (S-adenosyl-L-methionine, SAM)-competitive inhibitor of protein arginine N-methyltransferases (PRMTs; IC50 = 8.81 µM for PRMT1 and 3.03 for yeast-RMT1p) with minimal effect on lysine methyltransferases. Inhibits nuclear receptor reporter gene activation in MCF-7 cells, and HIV-1 RT polymerase (IC50 = 5 µM).
    产品目录编号 539209
    品牌系列 Calbiochem®
    同义词 PRMT Inhibitor I
    参考
    参考 Cheng, D., et al. 2004. J. Biol. Chem. 279, 23892.
    Skillman, A.G., et al. 2002. Bioorg. Chem. 30, 443.
    产品信息
    具有ATP竞争性 N
    形式 Solid
    Hill配方 C₂₁H₁₂N₂Na₄O₉S₂
    化学配方 C₂₁H₁₂N₂Na₄O₉S₂
    Molar Mass 592.4
    吸湿 Hygroscopic
    可逆 N
    结构配方图像
    生物信息
    主靶 Protein arginine N-methyltransferases (PRMTs)
    主靶IC50 8.81 µM for PRMT1 and 3.03 for yeast-RMT1p
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 H₂O
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,539209,Protein Arginine N-Methyltransferase Inhibitor, AMI-1 - Calbiochem

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